Cushing's syndrome classification: Difference between revisions
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Cushing's syndrome is classified into two main subtypes: | Cushing's syndrome is classified into two main subtypes: | ||
Exogenous: | *Exogenous: | ||
also called [[iatrogenic]] cushing's syndrome. It's due to taking [[glucocorticoids]] medications to treat inflammation caused by other diseases like allergies, [[asthma]], autoimmune diseases, and after organ transplantation. | :*also called [[iatrogenic]] cushing's syndrome. It's due to taking [[glucocorticoids]] medications to treat inflammation caused by other diseases like allergies, [[asthma]], autoimmune diseases, and after organ transplantation. | ||
Endogenous: | *Endogenous: | ||
It's due to tumors originating from withing the body. | :*It's due to tumors originating from withing the body. | ||
Benign tumors: | ::*Benign tumors: | ||
*Pituitary adenoma | :::*Pituitary adenoma | ||
*Adrenal adenoma | :::*Adrenal adenoma | ||
*Adrenal micronodular hyperplasia | :::*Adrenal micronodular hyperplasia | ||
*Adenomas in places other than the pituitary or adrenal glands, mostly in the lungs, pancreas, thyroid, or thymus | :::*Adenomas in places other than the pituitary or adrenal glands, mostly in the lungs, pancreas, thyroid, or thymus | ||
Malignant tumors: | ::*Malignant tumors: | ||
*Adrenal cancer | :::*Adrenal cancer | ||
*Cancer in places other than the pituitary or adrenal glands, mostly in the lungs, pancreas, thyroid, or thymus | :::*Cancer in places other than the pituitary or adrenal glands, mostly in the lungs, pancreas, thyroid, or thymus | ||
Familial Cushing's Syndrome | *Familial Cushing's Syndrome | ||
Patients with rare genetic diseases like multiple endocrine neoplasia type 1 and primary pigmented micronodular adrenal disease are more susceptible to develop tumors in glands that affect cortisol levels. As a result, these patients will develop cushing's syndrome. | :*Patients with rare genetic diseases like multiple endocrine neoplasia type 1 and primary pigmented micronodular adrenal disease are more susceptible to develop tumors in glands that affect cortisol levels. As a result, these patients will develop cushing's syndrome. | ||
*Pseudo-Cushing’s Syndrome | |||
:*It's due to alcoholism, depression or other psychiatric disorders, obesity, pregnancy, and poorly controlled diabetes. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 19:12, 1 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Cushing's syndrome may be classified according to the source of cortisol into two subtypes: endogenous and exogenous.
Classification
Cushing's syndrome is classified into two main subtypes:
- Exogenous:
- also called iatrogenic cushing's syndrome. It's due to taking glucocorticoids medications to treat inflammation caused by other diseases like allergies, asthma, autoimmune diseases, and after organ transplantation.
- Endogenous:
- It's due to tumors originating from withing the body.
- Benign tumors:
- Pituitary adenoma
- Adrenal adenoma
- Adrenal micronodular hyperplasia
- Adenomas in places other than the pituitary or adrenal glands, mostly in the lungs, pancreas, thyroid, or thymus
- Malignant tumors:
- Adrenal cancer
- Cancer in places other than the pituitary or adrenal glands, mostly in the lungs, pancreas, thyroid, or thymus
- Familial Cushing's Syndrome
- Patients with rare genetic diseases like multiple endocrine neoplasia type 1 and primary pigmented micronodular adrenal disease are more susceptible to develop tumors in glands that affect cortisol levels. As a result, these patients will develop cushing's syndrome.
- Pseudo-Cushing’s Syndrome
- It's due to alcoholism, depression or other psychiatric disorders, obesity, pregnancy, and poorly controlled diabetes.