Pheochromocytoma natural history, complications and prognosis: Difference between revisions
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==Complication== | ==Complication== | ||
The massive release of [[catecholamines]] in pheochromocytoma can cause damage to heart cells.<ref name=Goldman_327>{{Harvnb|Goldman|2011|pp=327}}</ref> This damage may be due to either compromising the [[coronary microcirculation]] or by direct toxic effects on the heart cells.<ref name=Goldman_327 /> | The massive release of [[catecholamines]] in pheochromocytoma can cause damage to heart cells.<ref name=Goldman_327>{{Harvnb|Goldman|2011|pp=327}}</ref> This damage may be due to either compromising the [[coronary microcirculation]] or by direct toxic effects on the heart cells.<ref name=Goldman_327 /> | ||
Other complication may include: | |||
*[[Hyperglycemia]] | |||
*[[Refractory hypertension]] | |||
*[[Malignant hypertension]] | |||
==Prognosis== | ==Prognosis== | ||
The 5-year survival in the setting of metastatic disease (whether identified at the time of initial diagnosis or identified postoperatively as recurrent disease) is 40% to 45% | The 5-year survival in the setting of metastatic disease (whether identified at the time of initial diagnosis or identified postoperatively as recurrent disease) is 40% to 45% | ||
Revision as of 14:08, 2 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Prognosis of pheochromocytoma is generally good but metastatic pheochromocytoma has a 5 year survival rate of approximately 45%.[1]. Massive release of catecholamines can causes damage to heart cells.
Complication
The massive release of catecholamines in pheochromocytoma can cause damage to heart cells.[2] This damage may be due to either compromising the coronary microcirculation or by direct toxic effects on the heart cells.[2] Other complication may include:
Prognosis
The 5-year survival in the setting of metastatic disease (whether identified at the time of initial diagnosis or identified postoperatively as recurrent disease) is 40% to 45%
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc
- ↑ 2.0 2.1 Goldman 2011, pp. 327