Gastrointestinal stromal tumor risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Risk factors

• Age-GIST's are more common in people aged 50 to 80
• Genetic syndromes:

• Neurofibromatosis type 1 (or von Recklinghausen disease
• Carney-Stratakis syndrome- People with this rare, inherited condition have an increased risk of GISTs, as well as nerve tumors called paragangliomas.
• Familial gastrointestinal stromal tumor syndrome- It is a rare, inherited condition that leads to an increased risk of developing GISTs.