21-hydroxylase deficiency classification: Difference between revisions
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'''Depending on severity:''' | '''Depending on severity:''' | ||
* Severe 21-hydroxylase deficiency causes '''''salt-wasting | * Severe 21-hydroxylase deficiency causes '''''salt-wasting congenital adrenal hyperplasia''''', with life-threatening vomiting and [[dehydration]] occurring within the first few weeks of life. Severe 21-hydroxylase deficiency is also the most common cause of [[ambiguous genitalia]] due to prenatal [[virilization]] of genetically female (XX) infants. | ||
* Moderate 21-hydroxylase deficiency is referred to as '''''simple virilizing | * Moderate 21-hydroxylase deficiency is referred to as '''''simple virilizing congenital adrenal hyperplasia'''''; and typically is recognized as causing virilization of prepubertal children. | ||
* Still milder forms of 21-hydroxylase deficiency are referred to as '''''non-classical | * Still milder forms of 21-hydroxylase deficiency are referred to as '''''non-classical congenital adrenal hyperplasia''''' and can cause [[androgen]] effects and [[infertility]] in adolescent and adult women. | ||
'''Depending on onset:''' | '''Depending on onset:''' | ||
* Early-onset: Severe 21-hydroxylase deficient | * Early-onset: Severe 21-hydroxylase deficient congenital adrenal hyperplasia | ||
* Childhood onset (simple virilizing) | * Childhood onset (simple virilizing) congenital adrenal hyperplasia | ||
* Late onset (nonclassical) | * Late onset (nonclassical) congenital adrenal hyperplasia | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Intersexuality]] | [[Category:Intersexuality]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 15:04, 3 September 2015
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Congenital adrenal hyperplasia due to 21-hydroxylase deficiency Microchapters |
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Differentiating Congenital adrenal hyperplasia due to 21-hydroxylase deficiency from other Diseases |
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Diagnosis |
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21-hydroxylase deficiency classification On the Web |
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American Roentgen Ray Society Images of 21-hydroxylase deficiency classification |
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Directions to Hospitals Treating Congenital adrenal hyperplasia due to 21-hydroxylase deficiency |
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Risk calculators and risk factors for 21-hydroxylase deficiency classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Classification
Depending on severity:
- Severe 21-hydroxylase deficiency causes salt-wasting congenital adrenal hyperplasia, with life-threatening vomiting and dehydration occurring within the first few weeks of life. Severe 21-hydroxylase deficiency is also the most common cause of ambiguous genitalia due to prenatal virilization of genetically female (XX) infants.
- Moderate 21-hydroxylase deficiency is referred to as simple virilizing congenital adrenal hyperplasia; and typically is recognized as causing virilization of prepubertal children.
- Still milder forms of 21-hydroxylase deficiency are referred to as non-classical congenital adrenal hyperplasia and can cause androgen effects and infertility in adolescent and adult women.
Depending on onset:
- Early-onset: Severe 21-hydroxylase deficient congenital adrenal hyperplasia
- Childhood onset (simple virilizing) congenital adrenal hyperplasia
- Late onset (nonclassical) congenital adrenal hyperplasia