21-hydroxylase deficiency secondary prevention: Difference between revisions

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{{Congenital adrenal hyperplasia due to 21-hydroxylase deficiency}}
{{Congenital adrenal hyperplasia due to 21-hydroxylase deficiency}}
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==Overview==
==Overview==
 
Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose is helpful in controlling fertility.
==Secondary Prevention==
==Secondary Prevention==
===Preventing hyperandrogenism and optimizing fertility===
===Preventing hyperandrogenism and optimizing fertility===
As growth ends, management in girls with CAH changes focus to optimizing reproductive function. Both excessive testosterone from the adrenals and excessive glucocorticoid treatment can disrupt [[ovulation]], resulting in irregularity of [[menstrual cycle|menses]] or [[amenorrhea]], as well as [[infertility]]. Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose can usually restore fertility, but as a group, women with CAH have a lower fertility rate than a comparable population.
Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose is helpful in controlling fertility, but as a group, women with CAH have a lower fertility rate than a comparable population.


CAH has little effect on male fertility unless an adult stops taking his glucocorticoid medication entirely for an extended period of time, in which case excessive adrenal testosterone may reduce testicular production as well as spermatogenesis.
== References ==
== References ==
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Revision as of 16:49, 4 September 2015

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose is helpful in controlling fertility.

Secondary Prevention

Preventing hyperandrogenism and optimizing fertility

Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose is helpful in controlling fertility, but as a group, women with CAH have a lower fertility rate than a comparable population.

References

Template:WikiDoc Sources