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| {{Familytree/end}} | | {{Familytree/end}} |
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| {| style="border: 0px; font-size: 90%; margin: 3px;" align=center
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| |+ ''' Reed-Sternberg cells (RSC) (Classical and variants) '''
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| ! style="background: #4479BA; color:#FFF;" | Type of cell
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| ! style="background: #4479BA; color:#FFF;" | Characteristics
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| | style="padding: 5px 5px; background: #DCDCDC;" colspan=3 | '''Classic'''
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| |-
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| | style="padding: 5px 5px; background: #F5F5F5;" | Reed-Sternberg cells (RSC)
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| | style="padding: 5px 5px; background: #F5F5F5;" | Include large size (20–50 micrometres), abundant, amphophilic, finely granular/homogeneous [[cytoplasm]]; two mirror-image [[nuclei]] (owl eyes) each with an eosinophilic [[nucleolus]] and a thick [[nuclear membrane]] ([[chromatin]] is distributed close to the nuclear membrane).
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| | style="padding: 5px 5px; background: #DCDCDC;" colspan=3 | '''Variants'''
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| |-
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| | style="padding: 5px 5px; background: #F5F5F5;" | Hodgkin cell
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| | style="padding: 5px 5px; background: #F5F5F5;" | (Atypical mononuclear Reed-Sternberg cell) has the same characteristics as Reed-Sternberg cells (RSC), but is mononucleated.
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| |-
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| | style="padding: 5px 5px; background: #F5F5F5;" | Lacunar Reed-Sternberg cells
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| | style="padding: 5px 5px; background: #F5F5F5;" | Are large, with a single hyperlobulated nucleus, multiple, small nucleoli and eosinophilic cytoplasm which is retracted around the nucleus, creating an empty space ("lacunae").
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| |-
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| | style="padding: 5px 5px; background: #F5F5F5;" | Pleomorphic Reed-Sternberg cells
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| | style="padding: 5px 5px; background: #F5F5F5;" | Has multiple irregular nuclei.
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| |-
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| | style="padding: 5px 5px; background: #F5F5F5;" | "Popcorn" Reed-Sternberg cells
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| | style="padding: 5px 5px; background: #F5F5F5;" | (Lympho-histiocytic variant) is a small cell, with a very lobulated nucleus, small nucleoli.
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| |-
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| | style="padding: 5px 5px; background: #F5F5F5;" | "Mummy" Reed-Sternberg cells
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| | style="padding: 5px 5px; background: #F5F5F5;" | has a compact nucleus with no nucleolus and basophilic cytoplasm.
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| |}
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