Adrenolipoma pathophysiology: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Adrenolipoma}} | {{Adrenolipoma}} | ||
{{CMG}} | {{CMG}} {{AE}} {{AAM}} | ||
==Pathophysiology== | ==Pathophysiology== | ||
A myelolipoma may represent a site of [[extramedullary hematopoiesis]]. The most widely accepted theory is the existence of [[metaplasia]] of the [[reticuloendothelial cells]] of blood [[capillaries]] in the [[adrenal gland]] in response to stimuli such as [[necrosis]], [[infection]], or [[stress]]. | A myelolipoma may represent a site of [[extramedullary hematopoiesis]]. The most widely accepted theory is the existence of [[metaplasia]] of the [[reticuloendothelial cells]] of blood [[capillaries]] in the [[adrenal gland]] in response to stimuli such as [[necrosis]], [[infection]], or [[stress]]. | ||
==Gross Pathology== | |||
Macroscopic examination demonstrates:<ref name="radiopaedia"> http://radiopaedia.org/articles/adrenal-myelolipoma </ref> | |||
Central congested, red to brown lesion with thin cortical rim. | |||
==Microscopic Pathology== | |||
Histological examination demonstrates:<ref name="radiopaedia"> http://radiopaedia.org/articles/adrenal-myelolipoma </ref> | |||
* Variable amounts of mature [[adipocytes]] (with distended lipid vacuoles) similar to [[bone marrow]] | |||
* Variable amounts of [[hematopoietic cells]] (including cells from myeloid, erythroid and megakaryocytic cells lines) | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Endocrine system]] | [[Category:Endocrine system]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Overview complete]] | [[Category:Overview complete]] | ||
Revision as of 14:39, 8 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Pathophysiology
A myelolipoma may represent a site of extramedullary hematopoiesis. The most widely accepted theory is the existence of metaplasia of the reticuloendothelial cells of blood capillaries in the adrenal gland in response to stimuli such as necrosis, infection, or stress.
Gross Pathology
Macroscopic examination demonstrates:[1]
Central congested, red to brown lesion with thin cortical rim.
Microscopic Pathology
Histological examination demonstrates:[1]
- Variable amounts of mature adipocytes (with distended lipid vacuoles) similar to bone marrow
- Variable amounts of hematopoietic cells (including cells from myeloid, erythroid and megakaryocytic cells lines)