Adrenolipoma pathophysiology

Adrenolipoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Adrenolipoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Adrenolipoma pathophysiology On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Adrenolipoma pathophysiology All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Adrenolipoma pathophysiology
CDC on Adrenolipoma pathophysiology
Adrenolipoma pathophysiology in the news
Blogs on Adrenolipoma pathophysiology
Directions to Hospitals Treating Adrenolipoma
Risk calculators and risk factors for Adrenolipoma pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Pathophysiology

A myelolipoma may represent a site of extramedullary hematopoiesis. The most widely accepted theory is the existence of metaplasia of the reticuloendothelial cells of blood capillaries in the adrenal gland in response to stimuli such as necrosis, infection, or stress.

Gross Pathology

Macroscopic examination demonstrates:

Central congested, red to brown lesion with thin cortical rim.

Microscopic Pathology

Histological examination demonstrates:

• Variable amounts of mature adipocytes (with distended lipid vacuoles) similar to bone marrow
• Variable amounts of hematopoietic cells (including cells from myeloid, erythroid and megakaryocytic cells lines)