Ganglioneuroma pathophysiology

Ganglioneuroma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Gross Pathology

• Ganglioneuromas are solid, firm tumors that are typically white when seen with the naked eye.
• Ganglioneuromas arise in the paravertebral sympathetic chains of the posterior mediastinum (41.5%) or retroperitoneum (37.5%).
• Less common sites include the adrenal gland (21%) and neck (8%).
• Paravertebral ganglioneuromas frequently extend through the neural foramina to involve the epidural space of the spinal canal.
• Intradural extramedullary ganglioneuromas are extremely rare.

Microscopic Pathology

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References

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