Aortitis natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, infectious aortitis is associated with a high rate of rupture and subsequent mortality. Aortitis due to either [[giant cell arteritis]] or [[Takayasu arteritis]] has a high rate of recurrence despite therapy.<ref name="pmid18541754">{{cite journal| author=Gornik HL, Creager MA| title=Aortitis. | journal=Circulation | year= 2008 | volume= 117 | issue= 23 | pages= 3039-51 | pmid=18541754 | doi=10.1161/CIRCULATIONAHA.107.760686 | pmc=PMC2759760 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18541754 }} </ref> Common complications of aortitis include: [[aortic aneurysm]], [[aortic rupture]], [[aortic dissection]], [[thrombus]] formation in the aortic lumen, and [[hypertension]] | If left untreated, infectious aortitis is associated with a high rate of rupture and subsequent mortality. Aortitis due to either [[giant cell arteritis]] or [[Takayasu arteritis]] has a high rate of recurrence despite therapy.<ref name="pmid18541754">{{cite journal| author=Gornik HL, Creager MA| title=Aortitis. | journal=Circulation | year= 2008 | volume= 117 | issue= 23 | pages= 3039-51 | pmid=18541754 | doi=10.1161/CIRCULATIONAHA.107.760686 | pmc=PMC2759760 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18541754 }} </ref> Common complications of aortitis include: [[aortic aneurysm]], [[aortic rupture]], [[aortic dissection]], [[thrombus]] formation in the aortic lumen, and [[hypertension]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] Associate Editor(s)-in-Chief: Maliha Shakil, M.D. [3]
Overview
If left untreated, infectious aortitis is associated with a high rate of rupture and subsequent mortality. Aortitis due to either giant cell arteritis or Takayasu arteritis has a high rate of recurrence despite therapy.[1] Common complications of aortitis include: aortic aneurysm, aortic rupture, aortic dissection, thrombus formation in the aortic lumen, and hypertension
Natural History
If untreated, aortitis has three distinct phases. The first phase is a prepulseless inflammatory stage with nonspecific symptoms such as fatigue, arthralgias, and low-grade fever. Phase two includes vascular inflammation with pain secondary to the condition, along with tenderness to palpation over the site. The last phase includes symptoms of ischemia and pain associated with the use of limbs. The limbs are cool and clammy in this stage.[2] If left untreated, infectious aortitis is associated with a high rate of rupture and subsequent mortality. Aortitis due to either giant cell arteritis or Takayasu arteritis has a high rate of recurrence despite therapy.[1]
Complications
Common complications of aortitis include:[1]
- Aortic aneurysm
- Aortic rupture
- Aortic dissection
- Thrombus formation in the aortic lumen
- Hypertension
Prognosis
References
- ↑ 1.0 1.1 1.2 Gornik HL, Creager MA (2008). "Aortitis". Circulation. 117 (23): 3039–51. doi:10.1161/CIRCULATIONAHA.107.760686. PMC 2759760. PMID 18541754.
- ↑ "Aortitis".