DRESS syndrome natural history, complications and prognosis: Difference between revisions
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*DRESS syndrome is characterized by a prolonged latency period. | *DRESS syndrome is characterized by a prolonged latency period. | ||
*Clinical manifestations of DRESS syndrome are usually delayed 2-8 weeks following the administration of triggering drug. | *Clinical manifestations of DRESS syndrome are usually delayed 2-8 weeks following the administration of triggering drug. | ||
*Initially, patients usually develop non-specific signs and symptoms, namely fever and rash. | *Initially, patients usually develop non-specific signs and symptoms, namely fever and rash. | ||
*Additional clinical manifestations follow, and patients may subsequently develop lymphadenopathy, visceral disease, and worsening of the skin eruption. | *Additional clinical manifestations follow, and patients may subsequently develop lymphadenopathy, visceral disease, and worsening of the skin eruption. | ||
*In the majority of cases, DRESS syndrome resolves following the discontinuation of triggering drug, but clinical manifestations may persist up to 3 months. | *In the majority of cases, DRESS syndrome resolves following the discontinuation of triggering drug, but clinical manifestations may persist up to 3 months. | ||
Revision as of 17:39, 17 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Natural History
- DRESS syndrome is characterized by a prolonged latency period.
- Clinical manifestations of DRESS syndrome are usually delayed 2-8 weeks following the administration of triggering drug.
- Initially, patients usually develop non-specific signs and symptoms, namely fever and rash.
- Additional clinical manifestations follow, and patients may subsequently develop lymphadenopathy, visceral disease, and worsening of the skin eruption.
- In the majority of cases, DRESS syndrome resolves following the discontinuation of triggering drug, but clinical manifestations may persist up to 3 months.