DRESS syndrome primary prevention: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{DRESS syndrome}} | {{DRESS syndrome}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{YD}}; {{SSK}} | ||
==Overview== | ==Overview== | ||
There are no established measures for the primary prevention of DRESS syndrome. Primary prevention measures may include slow dose escalation of drugs (e.g. anticonvulsants), genetic counseling, and ''in vitro'' impaired detoxification testing. | |||
==Primary Prevention== | ==Primary Prevention== | ||
There are no established measures for the primary prevention of DRESS syndrome. Primary prevention measures may include the following: | |||
*Slow dose escalation of agents known to be associated with DRESS syndrome<ref name="pmid8536554">{{cite journal| author=Fitton A, Goa KL| title=Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy. | journal=Drugs | year= 1995 | volume= 50 | issue= 4 | pages= 691-713 | pmid=8536554 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8536554 }} </ref> | |||
*Genetic counseling to relatives of patients with DRESS syndrome<ref name="pmid10730749">{{cite journal| author=Sullivan JR, Shear NH| title=What are some of the lessons learnt from in vitro studies of severe unpredictable drug reactions? | journal=Br J Dermatol | year= 2000 | volume= 142 | issue= 2 | pages= 205-7 | pmid=10730749 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10730749 }} </ref> | |||
*''In vitro'' impaired detoxification testing using lymphocyte toxicity assays among individuals with affected first-degree relatives<ref name="pmid10730749">{{cite journal| author=Sullivan JR, Shear NH| title=What are some of the lessons learnt from in vitro studies of severe unpredictable drug reactions? | journal=Br J Dermatol | year= 2000 | volume= 142 | issue= 2 | pages= 205-7 | pmid=10730749 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10730749 }} </ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:28, 21 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.
Overview
There are no established measures for the primary prevention of DRESS syndrome. Primary prevention measures may include slow dose escalation of drugs (e.g. anticonvulsants), genetic counseling, and in vitro impaired detoxification testing.
Primary Prevention
There are no established measures for the primary prevention of DRESS syndrome. Primary prevention measures may include the following:
- Slow dose escalation of agents known to be associated with DRESS syndrome[1]
- Genetic counseling to relatives of patients with DRESS syndrome[2]
- In vitro impaired detoxification testing using lymphocyte toxicity assays among individuals with affected first-degree relatives[2]
References
- ↑ Fitton A, Goa KL (1995). "Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy". Drugs. 50 (4): 691–713. PMID 8536554.
- ↑ 2.0 2.1 Sullivan JR, Shear NH (2000). "What are some of the lessons learnt from in vitro studies of severe unpredictable drug reactions?". Br J Dermatol. 142 (2): 205–7. PMID 10730749.