DRESS syndrome history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.

Overview

Common symptoms of DRESS syndrome rash and fever.

History and Symptoms

Symptoms of DRESS syndrome include the following:

Most Common Symptoms

• Rash (almost always present, may be pruritic)
• Fever (present in approximately 80% of patients)
• Fatigue

Other Symptoms

• Myalgia
• Facial edema
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Cough
• Sore throat
• Dyspnea
• Bruise
• Epistaxis
• Oral and perioral pain (caused by mucosal lesions in the oral cavity)
• Confusion