Multiple myeloma epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.<ref>Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1</ref> The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.<ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology</ref> Multiple myeloma is the second most common blood cancer after [[non-Hodgkin's lymphoma]] & 14th most common cancer overall in United States.<ref name="Collins-2005">{{Cite journal  | last1 = Collins | first1 = CD. | title = Problems monitoring response in multiple myeloma. | journal = Cancer Imaging | volume = 5 Spec No A | issue =  | pages = S119-26 | month =  | year = 2005 | doi = 10.1102/1470-7330.2005.0033 | PMID = 16361127 }}</ref><ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>  Male are more commonly affected with multiple myeloma than female. The male to female ratio is approximately 2 to 1.<ref>Multiplemyeloma.Wikipedia(2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref> Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.<ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> The incidence of multiple myeloma increases with age; the median age at diagnosis is between 65 to 70 years years.<ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>
In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.<ref>Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1</ref> The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.<ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology</ref> Multiple myeloma is the second most common blood cancer after [[non-Hodgkin's lymphoma]] & 14th most common cancer overall in United States.<ref name="Collins-2005">{{Cite journal  | last1 = Collins | first1 = CD. | title = Problems monitoring response in multiple myeloma. | journal = Cancer Imaging | volume = 5 Spec No A | issue =  | pages = S119-26 | month =  | year = 2005 | doi = 10.1102/1470-7330.2005.0033 | PMID = 16361127 }}</ref><ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>  Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 1.54 to 1.<ref>Multiplemyeloma.Wikipedia(2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref> Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.<ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> The incidence of multiple myeloma increases with age; the median age at diagnosis is between 65 to 70 years.<ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>


==Epidemiology and Demographics==
==Epidemiology and Demographics==
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*In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.<ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>
*In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.<ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>
===Age===
===Age===
*The incidence of multiple myeloma increases with age; the median age at diagnosis is is 65 to 70 years. Though recent statistics indicate an increase in incidence of earlier age of onset in multiple myeloma.<ref>Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015</ref>
*The incidence of multiple myeloma increases with age; the median age at diagnosis is is 65 to 70 years. Recent statistics concerning earlier age of onset in multiple myelom indicate an increase in incidence among the population.<ref>Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015</ref>
*Multiple myeloma is a common malignancy of older patients above 40 years old (70% of cases are diagnosed between 50 and 70 years of age.<ref>Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref>)
*Multiple myeloma is a common malignancy of older patients above 40 years old (70% of cases are diagnosed between 50 and 70 years of age.<ref>Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref>)


Line 29: Line 29:
===Race===
===Race===
*Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian and Native Indian individuals are less likely to develop multiple myeloma.<ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>
*Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian and Native Indian individuals are less likely to develop multiple myeloma.<ref>Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>
*Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer death. <ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>
*Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer deaths. <ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>


==Gallery==
==Gallery==

Revision as of 17:38, 22 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.[1] The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.[2][3] Multiple myeloma is the second most common blood cancer after non-Hodgkin's lymphoma & 14th most common cancer overall in United States.[4][5][6] Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 1.54 to 1.[7][8] Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.[9] The incidence of multiple myeloma increases with age; the median age at diagnosis is between 65 to 70 years.[10]

Epidemiology and Demographics

Incidence

  • In 2012, the incidence of multiple myeloma waws approximately 6.3 per 100,000 individuals with a case-fatality rate of 3.3 per 100,000 in the United States.[11]
  • In 2014, multiple myeloma constituted approximately 1.4 percent of the estimated new cancer cases.[12]
  • In 2015, the estimated incidence of multiple myeloma is 1.6% of all new cancer cases and 1.9% of all cancer mortality cases.[13]
  • Multiple myeloma is the 14th leading cause of cancer death in the United States.[14]
  • Since 1975, the overall multiple myeloma incidence has increased nearly 1 percent annually.[15]

Prevalance

  • Myeloma is the 14th leading cause of cancer death in the United States.[16]
  • Multiple myeloma is the second most prevalent blood cancer (10%) after non-Hodgkin's lymphoma.[4][17]
  • There are approximately 76,000 people in the United States living with multiple myeloma. [18]
  • Multiple myeloma represents approximately 1% of all cancers and 2% of all cancer deaths.[19]
  • In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.[20]

Age

  • The incidence of multiple myeloma increases with age; the median age at diagnosis is is 65 to 70 years. Recent statistics concerning earlier age of onset in multiple myelom indicate an increase in incidence among the population.[21]
  • Multiple myeloma is a common malignancy of older patients above 40 years old (70% of cases are diagnosed between 50 and 70 years of age.[22])

Gender

  • Male are more commonly affected with multiple myeloma than female. The male to female ratio is approximately 2 to 1.[23]

Race

  • Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian and Native Indian individuals are less likely to develop multiple myeloma.[24]
  • Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer deaths. [25]

Gallery

Multiple myeloma summary.[26]


Percent of new cases by age group: multiple myeloma.[27]


Number of new cases per 100,000 persons by race/ethnicity & sex: multiple myeloma.[28]


Percent of deaths per age group: multiple myeloma.[29]


Number of deaths per 100,000 persons by race/ethnicity & sex multiple myeloma.[30]


Multiple myeloma percent of total new cancer csases in the United states.[31]


Five year survival percentage.[32]


New cases, deaths, and 5-Year relative survival.[33]

References

  1. ↑ Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1
  2. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  3. ↑ Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology
  4. ↑ 4.0 4.1 Collins, CD. (2005). "Problems monitoring response in multiple myeloma". Cancer Imaging. 5 Spec No A: S119–26. doi:10.1102/1470-7330.2005.0033. PMID 16361127.
  5. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  6. ↑ Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  7. ↑ Multiplemyeloma.Wikipedia(2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  8. ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  9. ↑ Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  10. ↑ Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  11. ↑ Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1
  12. ↑ A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma Accessed on September, 20th 2015
  13. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  14. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  15. ↑ A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma
  16. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  17. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  18. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  19. ↑ Multiple myeloma. Wikipedia (2015) https://en.wikipedia.org/wiki/Multiple_myeloma. Accessed on September, 20th 2015
  20. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  21. ↑ Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015
  22. ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  23. ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  24. ↑ Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  25. ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  26. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  27. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  28. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  29. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  30. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  31. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  32. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015
  33. ↑ SEER Stat Fact Sheets: Myeloma. Surveillance, Epidemiology, and End Results Program Turning Cancer Data Into Discovery.http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September ,20 2015

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