Carcinoid syndrome causes: Difference between revisions

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:*Most carcinoids associated with [[multiple endocrine neoplasia type 1]] appear to be of foregut origin.
:*Most carcinoids associated with [[multiple endocrine neoplasia type 1]] appear to be of foregut origin.
:* Carcinoids in patients with [[neurofibromatosis type 1]] appear to arise primarily in the periampullary region.
:* Carcinoids in patients with [[neurofibromatosis type 1]] appear to arise primarily in the periampullary region.
*In sporadic gastrointestinal carcinoids, numerous [[chromosomal imbalances]] have been found by comparative genome hybridization analysis. Gains involving chromosomes 5, 14, 17 (especially 17q), and 19 and losses involving chromosomes 11 (especially 11q) and 18 appear to be the most common.
*In sporadic gastrointestinal carcinoids, numerous chromosomal imbalances have been found by comparative genome hybridization analysis. Gains involving chromosomes 5, 14, 17 (especially 17q), and 19 and losses involving chromosomes 11 (especially 11q) and 18 appear to be the most common.


==References==
==References==

Revision as of 14:37, 25 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Causes

  • In sporadic gastrointestinal carcinoids, numerous chromosomal imbalances have been found by comparative genome hybridization analysis. Gains involving chromosomes 5, 14, 17 (especially 17q), and 19 and losses involving chromosomes 11 (especially 11q) and 18 appear to be the most common.

References

  1. Molecular genetics . National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq Accessed on September 22, 2015

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