Carcinoid syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

The prevalence of carcinoid syndrome is approximately 1.5 per 100,000 individuals worldwide. The median age at diagnosis is 61.4 years.

Epidemiology and Demographics

• Carcinoid syndrome is quite rare with a disease prevalence of 15 cases per 1,000,000 people.
• The age-adjusted incidence of carcinoid tumors worldwide is approximately 2 per 100,000 persons.
• The average age at diagnosis is 61.4 years.
• Carcinoid tumors represent about 0.5% of all newly diagnosed malignancies.
• Carcinoid tumors account for 75% of all gastrointestinal endocrine tumors.
• Ovarian carcinoid tumors account for 0.3% of all ovarian tumours and 0.5% of carcinoid tumours.
• Ovarian carcinoid tumors are commonly seen in perimenopausal and postmenopausal women.
• Primary hepatic carcinoid is an extremely rare type of carcinoid tumor, with somewhere between 60-90 cases reported in the literature.
• Thymic carcinoid tumors are more predominant in males, with male to female ratios around 3:1.