Meningioma risk factors: Difference between revisions

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==Overview==
==Overview==
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==Risk Factors==
==Risk Factors==
*Common risk factors in the development of meningioma are history of radiation treatment, inherited nervous system disorder, and female gender.<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343  }} </ref>


The table below lists the risk factors for multiple myeloma:
*The table below lists the risk factors for meningioma development:


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Age'''|| style="padding: 5px 5px; background: #F5F5F5;" |The chance to develop multiple myeloma increases as patients get older, where only 1% of multiple myeloma cases are diagnosed in patients younger than 35 years.<ref name="press">Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015</ref><ref name="radio">Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Radiation treatment'''|| style="padding: 5px 5px; background: #F5F5F5;" |Head radiation therapy and dental X-ray are correlated with an increased risk of meningioma<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343  }} </ref>  


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Race'''|| style="padding: 5px 5px; background: #F5F5F5;" |African American and Native Pacific Islanders descents are at increased risk of developing multiple myeloma.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref><ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Inherited nervous system disorder'''|| style="padding: 5px 5px; background: #F5F5F5;" |Neurofibromatosis type 2 increases the risk of meningioma<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343  }} </ref>


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Gender'''|| style="padding: 5px 5px; background: #F5F5F5;" |Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 2 to 1.<ref name="radio">Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Gender'''|| style="padding: 5px 5px; background: #F5F5F5;" |Female hormones play an important role in meningioma development<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343  }} </ref>  
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Having other plasma cell diseases'''|| style="padding: 5px 5px; background: #F5F5F5;" |Patients with other [[plasma cell]] diseases such as [[monoclonal gammopathy of undetermined significance]]  develop multiple myeloma later in their lives.<ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit&section=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Family history'''|| style="padding: 5px 5px; background: #F5F5F5;" |A familial predisposition to myeloma exists due to [[hyperphosphorylation]] of specific proteins that may contribute to a higher rates of multiple myeloma in certain groups.<ref name="Bourguet-1985">{{Cite journal  | last1 = Bourguet | first1 = CC. | last2 = Grufferman | first2 = S. | last3 = Delzell | first3 = E. | last4 = DeLong | first4 = ER. | last5 = Cohen | first5 = HJ. | title = Multiple myeloma and family history of cancer. A case-control study. | journal = Cancer | volume = 56 | issue = 8 | pages = 2133-9 | month = Oct | year = 1985 | doi =  | PMID = 4027940 }}</ref><ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref name="pmid23926460">{{cite journal| author=Koura DT, Langston AA| title=Inherited predisposition to multiple myeloma. | journal=Ther Adv Hematol | year= 2013 | volume= 4 | issue= 4 | pages= 291-7 | pmid=23926460 | doi=10.1177/2040620713485375 | pmc=PMC3734900 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23926460 }} </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Cell phone use'''|| style="padding: 5px 5px; background: #F5F5F5;" |Heavy cell phone use has been associated with increased risk of meningioma<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343 }} </ref>


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Obesity'''|| style="padding: 5px 5px; background: #F5F5F5;" | Being overweight increases a person's risk of developing multiple myeloma.<ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit&section=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Head trauma'''|| style="padding: 5px 5px; background: #F5F5F5;" | A positive history of head trauma increases the risk of meningioma<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343  }} </ref>  
 
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Workplace exposures'''|| style="padding: 5px 5px; background: #F5F5F5;" |Petroleum workers and farmers tend to have higher incidence of multiple myeloma relative to other occupations.<ref name="Gallagher-1983">{{Cite journal | last1 = Gallagher | first1 = RP. | last2 = Spinelli | first2 = JJ. | last3 = Elwood | first3 = JM. | last4 = Skippen | first4 = DH. | title = Allergies and agricultural exposure as risk factors for multiple myeloma. | journal = Br J Cancer | volume = 48 | issue = 6 | pages = 853-7 | month = Dec | year = 1983 | doi = | PMID = 6652026 }}</ref><ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit&section=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Radiation'''|| style="padding: 5px 5px; background: #F5F5F5;" | Areas with previous history of atoms bombs or nuclear accidents had higher risk of multiple myeloma due to increased rate of radiation exposure.<ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit&section=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref>
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:*Radiation treatment: Clinical data suggests that head radiation therapy increase the risk of developing meningioma.
 
:*An inherited nervous system disorder: Studies show the rare disorder neurofibromatosis type 2 increases the risk of meningioma and other brain tumors.
:*Female hormones: As a tumor common in women than men, doctors believe that female hormones may play an important role in developing meningioma.


==References==
==References==

Revision as of 18:21, 25 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Common risk factors in the development of meningioma are history of radiation treatment, inherited nervous system disorder, and female gender.[1][2][3]

Risk Factors

  • Common risk factors in the development of meningioma are history of radiation treatment, inherited nervous system disorder, and female gender.[1][2][3]
  • The table below lists the risk factors for meningioma development:
Risk Factor Description
Radiation treatment Head radiation therapy and dental X-ray are correlated with an increased risk of meningioma[1][2][3]
Inherited nervous system disorder Neurofibromatosis type 2 increases the risk of meningioma[1][2][3]
Gender Female hormones play an important role in meningioma development[1][2][3]
Cell phone use Heavy cell phone use has been associated with increased risk of meningioma[1][2][3]
Head trauma A positive history of head trauma increases the risk of meningioma[1][2][3]


References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Wiemels J, Wrensch M, Claus EB (2010). "Epidemiology and etiology of meningioma". J Neurooncol. 99 (3): 307–14. doi:10.1007/s11060-010-0386-3. PMC 2945461. PMID 20821343.


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