Osteosarcoma risk factors: Difference between revisions
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{{Osteosarcoma}} | {{Osteosarcoma}} | ||
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==Overview== | ==Overview== | ||
The common risk factors in the development of osteosarcoma are radiation to bones, [[alkylating antineoplastic agents]], [[paget disease]], Multiple hereditary [[osteochondromas]], [[Fibrous dysplasia]], [[Bloom syndrome]],[[Rothmund-Thomson syndrome]], and [[Li-Fraumeni syndrome]]. | |||
==Risk Factors== | ==Risk Factors== | ||
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:*[[Familial adenomatous polyposis]] | :*[[Familial adenomatous polyposis]] | ||
:*[[Li-Fraumeni syndrome]] | :*[[Li-Fraumeni syndrome]] | ||
:*[[Retinoblastoma|Hereditary retinoblastoma]] | :*[[Retinoblastoma|Hereditary retinoblastoma]] | ||
:*[[Rothmund-Thomson syndrome]] | :*[[Rothmund-Thomson syndrome]] | ||
Revision as of 19:08, 28 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The common risk factors in the development of osteosarcoma are radiation to bones, alkylating antineoplastic agents, paget disease, Multiple hereditary osteochondromas, Fibrous dysplasia, Bloom syndrome,Rothmund-Thomson syndrome, and Li-Fraumeni syndrome.
Risk Factors
- Age and height: Data suggest that the risk of osteosarcoma is highest during the teenage "growth spurt." Children with osteosarcoma are usually tall for their age.
- Radiation to bones: People who were treated with radiation for another cancer have a higher risk of later developing post-radiation (after radiation) osteosarcoma.
- Drugs: Past treatment with anticancer drugs called alkylating antineoplastic agents.
- Certain bone diseases:
- Paget disease of bone
- Multiple hereditary osteochondromas
- Fibrous dysplasia
- Enchondromtosis.
- Inherited cancer syndromes: Genetic diseases that Predispose to osteosarcoma are: