Burkitt's lymphoma medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
==Medical Therapy== | ==Medical Therapy== | ||
===Chemotherapy=== | ===Chemotherapy=== | ||
* [[ | * Drug Regimen: (CODOX-M) [[Cyclophosphamide]], {{and}} [[Vincristine]], {{and}} [[Doxorubicin]], {{and}} [[Methotrexate]] | ||
* [[ | * Drug Regimen: (IVAC) [[Ifosfamide]] {{plus}} [[Mesna]], {{and}} [[Etoposide]], {{and}} [[Cytarabine]] | ||
* [[ | * Drug Regimen: (Hyper-CVAD) [[Cyclophosphamide]], {{and}} [[Vincristine]], {{and}} [[Doxorubicin]], {{and}} [[Dexamethasone]], {{and}} [[Methotrexate]], {{and}} [[Cytarabine]] | ||
===Biological therapy=== | |||
* [[ | * Monoclonal antibodies are a type of biological therapy that is effective in treating Burkitt's lymphoma | ||
* [[ | * [[Rituximab]] may be added to each of the above chemotherapy regimens | ||
===CNS prophylaxis=== | |||
* There is a high risk that Burkitt's lymphoma will spread to the central nervous system (CNS) | |||
* CNS prophylaxis may involve giving intrathecal chemotherapy high doses of systemic therapy, or both methods may be used | |||
* [[Methotrexate]] and [[Cytarabine]] are the drugs used most often for CNS prophylaxis | |||
===Stem cell transplant=== | |||
* A Stem cell transplant may be offered to some people with Burkitt's lymphoma if their lymphoma returns or relapses after treatment | |||
==References== | ==References== |
Revision as of 20:18, 28 September 2015
Burkitt's lymphoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Medical Therapy
Chemotherapy
- Drug Regimen: (CODOX-M) Cyclophosphamide, AND Vincristine, AND Doxorubicin, AND Methotrexate
- Drug Regimen: (IVAC) Ifosfamide PLUS Mesna, AND Etoposide, AND Cytarabine
- Drug Regimen: (Hyper-CVAD) Cyclophosphamide, AND Vincristine, AND Doxorubicin, AND Dexamethasone, AND Methotrexate, AND Cytarabine
Biological therapy
- Monoclonal antibodies are a type of biological therapy that is effective in treating Burkitt's lymphoma
- Rituximab may be added to each of the above chemotherapy regimens
CNS prophylaxis
- There is a high risk that Burkitt's lymphoma will spread to the central nervous system (CNS)
- CNS prophylaxis may involve giving intrathecal chemotherapy high doses of systemic therapy, or both methods may be used
- Methotrexate and Cytarabine are the drugs used most often for CNS prophylaxis
Stem cell transplant
- A Stem cell transplant may be offered to some people with Burkitt's lymphoma if their lymphoma returns or relapses after treatment