Burkitt's lymphoma classification: Difference between revisions
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| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Endemic Burkitt's lymphoma''' | | style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Endemic Burkitt's lymphoma''' | ||
(African Burkitt's lymphoma) | |||
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* The most common childhood cancer in Africa | * The most common childhood cancer in Africa | ||
* Almost always associated with Epstein-Barr virus infection | * Almost always associated with [[Epstein-Barr virus]] infection | ||
* Characteristically involves the jaw or other facial bone, distal ileum, cecum, ovaries, kidney or the breast | * Characteristically involves the jaw or other [[facial bone]], [[distal ileum]], [[cecum]], [[ovaries]], kidney or the breast | ||
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| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Sporadic Burkitt's lymphoma''' | | style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Sporadic Burkitt's lymphoma''' | ||
(Non-African or Non-endemic Burkitt's lymphoma) | |||
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* The most common type of Burkitt's lymphoma in North America and European countries | * The most common type of Burkitt's lymphoma in North America and European countries | ||
* Sometimes associated with the [[Epstein-Barr virus]], but in many cases this virus is not present | * Sometimes associated with the [[Epstein-Barr virus]], but in many cases this virus is not present | ||
* Non- | * [[Non-Hodgkin's]], which includes Burkitt's, accounts for 30-50% of childhood lymphoma | ||
* Ileo-cecal region is the common site of involvement | * Ileo-cecal region is the common site of involvement | ||
* Most often starts in the abdomen, but can also start in the ovaries, testicles, kidneys or other organs | * Most often starts in the abdomen, but can also start in the ovaries, testicles, kidneys or other organs | ||
* Jaw is less commonly involved, comparing with the endemic variant | * Jaw is less commonly involved, comparing with the endemic variant | ||
* Can also involve the pleura lining the lung, central nervous system (CNS) and, uncommonly, the breast | * Can also involve the pleura lining the lung, [[central nervous system]] (CNS) and, uncommonly, the breast | ||
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| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Immunodeficiency-associated Burkitt's lymphoma''' | | style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Immunodeficiency-associated Burkitt's lymphoma''' | ||
Revision as of 13:28, 29 September 2015
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Burkitt's lymphoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Burkitt's lymphoma classification On the Web |
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American Roentgen Ray Society Images of Burkitt's lymphoma classification |
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Risk calculators and risk factors for Burkitt's lymphoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Burkitt's lymphoma may be classified into 3 clinical variants: endemic Burkitt's lymphoma, sporadic Burkitt's lymphoma, and immunodeficiency-associated Burkitt's lymphoma.
Classification
Burkitt's lymphoma may be classified into 3 clinical variants:[1]
- Endemic Burkitt's lymphoma
- Sporadic Burkitt's lymphoma
- Immunodeficiency-associated Burkitt's lymphoma
By morphology (i.e. microscopic appearance) or immunophenotype, it is almost impossible to differentiate these three clinical variants. Immunodeficiency-associated Burkitt's lymphoma may demonstrate more plasmacytic appearance or more pleomorphism, but these features are not specific.
| Name | Description |
|---|---|
| Endemic Burkitt's lymphoma
(African Burkitt's lymphoma) |
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| Sporadic Burkitt's lymphoma
(Non-African or Non-endemic Burkitt's lymphoma) |
|
| Immunodeficiency-associated Burkitt's lymphoma |
|
References
- ↑ Burkitt lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/burkitt-lymphoma/?region=on Accessed on September 29, 2015