Tumor lysis syndrome differential diagnosis: Difference between revisions
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Tumor lysis syndrome must be differentiated from other diseases that cause [[hyperuricemia]], [[hyperkalemia]], and [[hyperphosphatemia]], such as [[acute kidney injury]].<ref name="pmid24359983">{{cite journal| author=Wilson FP, Berns JS| title=Tumor lysis syndrome: new challenges and recent advances. | journal=Adv Chronic Kidney Dis | year= 2014 | volume= 21 | issue= 1 | pages= 18-26 | pmid=24359983 | doi=10.1053/j.ackd.2013.07.001 | pmc=PMC4017246 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24359983 }} </ref> | Tumor lysis syndrome must be differentiated from other diseases that cause [[hyperuricemia]], [[hyperkalemia]], and [[hyperphosphatemia]], such as [[acute kidney injury]].<ref name="pmid24359983">{{cite journal| author=Wilson FP, Berns JS| title=Tumor lysis syndrome: new challenges and recent advances. | journal=Adv Chronic Kidney Dis | year= 2014 | volume= 21 | issue= 1 | pages= 18-26 | pmid=24359983 | doi=10.1053/j.ackd.2013.07.001 | pmc=PMC4017246 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24359983 }} </ref> | ||
==Differentiating tumor lysis syndrome from other Diseases== | ==Differentiating tumor lysis syndrome from other Diseases== | ||
Tumor lysis syndrome must be differentiated from other diseases that cause electrolytes disturbance. | Tumor lysis syndrome must be differentiated from other diseases that cause electrolytes disturbance.<ref name="pmid24359983">{{cite journal| author=Wilson FP, Berns JS| title=Tumor lysis syndrome: new challenges and recent advances. | journal=Adv Chronic Kidney Dis | year= 2014 | volume= 21 | issue= 1 | pages= 18-26 | pmid=24359983 | doi=10.1053/j.ackd.2013.07.001 | pmc=PMC4017246 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24359983 }} </ref> | ||
*[[Hyperuricemia]]:<ref name="wikipedia">Wikipedia.https://en.wikipedia.org/wiki/Hyperuricemia</ref> | *[[Hyperuricemia]]:<ref name="wikipedia">Wikipedia.https://en.wikipedia.org/wiki/Hyperuricemia</ref> | ||
:*Hereditary hyperuricemia | :*Hereditary hyperuricemia | ||
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::*Type IV [[renal tubular acidosis]] | ::*Type IV [[renal tubular acidosis]] | ||
:*Gordon's syndrome ([[pseudohypoaldosteronism]] type II) | :*Gordon's syndrome ([[pseudohypoaldosteronism]] type II) | ||
*[[Hyperphosphatemia]] | *[[Hyperphosphatemia]]<ref name="wikipedia">Wikipedia.https://en.wikipedia.org/wiki/Hyperphosphatemia</ref> | ||
:*[[Acute kidney injury]] | :*[[Acute kidney injury]] | ||
:*[[Hypoparathyroidism]] | :*[[Hypoparathyroidism]] | ||
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::*[[Rhabdomyolysis]] | ::*[[Rhabdomyolysis]] | ||
::*[[Hyperthermia]] | ::*[[Hyperthermia]] | ||
::*[[Fulminant hepatitis]] | |||
::*Severe [[hemolytic anemia]] | |||
:*Transcellular phosphate shifts: | |||
::*[[Metabolic acidosis]] | |||
::*[[Respiratory acidosis]] | |||
<ref name="pmid24359983">{{cite journal| author=Wilson FP, Berns JS| title=Tumor lysis syndrome: new challenges and recent advances. | journal=Adv Chronic Kidney Dis | year= 2014 | volume= 21 | issue= 1 | pages= 18-26 | pmid=24359983 | doi=10.1053/j.ackd.2013.07.001 | pmc=PMC4017246 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24359983 }} </ref> | <ref name="pmid24359983">{{cite journal| author=Wilson FP, Berns JS| title=Tumor lysis syndrome: new challenges and recent advances. | journal=Adv Chronic Kidney Dis | year= 2014 | volume= 21 | issue= 1 | pages= 18-26 | pmid=24359983 | doi=10.1053/j.ackd.2013.07.001 | pmc=PMC4017246 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24359983 }} </ref> | ||
Revision as of 19:33, 29 September 2015
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Tumor lysis syndrome Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Tumor lysis syndrome differential diagnosis On the Web |
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American Roentgen Ray Society Images of Tumor lysis syndrome differential diagnosis |
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Risk calculators and risk factors for Tumor lysis syndrome differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Tumor lysis syndrome must be differentiated from other diseases that cause hyperuricemia, hyperkalemia, and hyperphosphatemia, such as acute kidney injury.[1]
Differentiating tumor lysis syndrome from other Diseases
Tumor lysis syndrome must be differentiated from other diseases that cause electrolytes disturbance.[1]
- Hereditary hyperuricemia
- Insulin resistance
- Hypertension
- Obesity
- Gout
- Alcoholism
- Renal insufficiency
- Medications:
- Renal insufficiency
- Medications
- ACE inhibitor
- angiotensin receptor blockers
- Potassium-sparing diuretics such asamiloride and spironolactone
- NSAIDs such as ibuprofen andnaproxen
- Ciclosporin
- Tacrolimus
- Antibiotics such as trimethoprim
- Antiparasitic drugs such as pentamidine
- Mineralocorticoid deficiency or resistance, such as:
- Addison's disease
- Aldosterone deficiency
- Some forms of congenital adrenal hyperplasia
- Type IV renal tubular acidosis
- Gordon's syndrome (pseudohypoaldosteronism type II)
- Acute kidney injury
- Hypoparathyroidism
- Vitamin D
- vitamin A intoxication
- Sarcoidosis
- Immobilization
- Osteolytic metastases
- Milk-alkali syndrome
- Severe hypermagnesemia or hypomagnesemia
- Pseudohypoparathyroidism
- Acromegaly
- Extensive cellular injury or necrosis:
- Crush injury
- Rhabdomyolysis
- Hyperthermia
- Fulminant hepatitis
- Severe hemolytic anemia
- Transcellular phosphate shifts:
References
- ↑ 1.0 1.1 1.2 Wilson FP, Berns JS (2014). "Tumor lysis syndrome: new challenges and recent advances". Adv Chronic Kidney Dis. 21 (1): 18–26. doi:10.1053/j.ackd.2013.07.001. PMC 4017246. PMID 24359983.
- ↑ 2.0 2.1 2.2 Wikipedia.https://en.wikipedia.org/wiki/Hyperuricemia