Medulloblastoma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Medulloblastoma may be classified into several subtypes based on WHO 2007 histological classification system (desmoplastic/nodular medulloblastoma, large cell medulloblastoma, anaplastic medulloblastoma, and medulloblastoma with extensive nodularity) and the molecular subtypes classification system ( | Medulloblastoma may be classified into several subtypes based on WHO 2007 histological classification system (desmoplastic/nodular medulloblastoma, large cell medulloblastoma, anaplastic medulloblastoma, and medulloblastoma with extensive nodularity) and the molecular subtypes classification system (Wnt group, SHH group, Group C, and Group D).<ref name="pmid17618441">{{cite journal| author=Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A et al.| title=The 2007 WHO classification of tumours of the central nervous system. | journal=Acta Neuropathol | year= 2007 | volume= 114 | issue= 2 | pages= 97-109 | pmid=17618441 | doi=10.1007/s00401-007-0243-4 | pmc=PMC1929165 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17618441 }} </ref><ref name="pmid22189395">Leary SE, Olson JM (2012) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=22189395 The molecular classification of medulloblastoma: driving the next generation clinical trials.] ''Curr Opin Pediatr'' 24 (1):33-9. [http://dx.doi.org/10.1097/MOP.0b013e32834ec106 DOI:10.1097/MOP.0b013e32834ec106] PMID: [http://pubmed.gov/22189395 22189395]</ref><ref name="patho">Medulloblastoma. Librepathology(2015) http://librepathology.org/wiki/index.php/Medulloblastoma Accessed on September, 28th 2015</ref><ref name="radio">Medulloblastoma. radiopaedia(2015) http://radiopaedia.org/articles/medulloblastoma Accessed on September, 28th 2015</ref> | ||
==Classification== | ==Classification== | ||
Revision as of 23:49, 29 September 2015
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Medulloblastoma Microchapters |
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Medulloblastoma classification On the Web |
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American Roentgen Ray Society Images of Medulloblastoma classification |
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Risk calculators and risk factors for Medulloblastoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Medulloblastoma may be classified into several subtypes based on WHO 2007 histological classification system (desmoplastic/nodular medulloblastoma, large cell medulloblastoma, anaplastic medulloblastoma, and medulloblastoma with extensive nodularity) and the molecular subtypes classification system (Wnt group, SHH group, Group C, and Group D).[1][2][3][4]
Classification
WHO 2007 histological classification system | |||||||||||||||||||||||||||||||||||||||
Desmoplastic medulloblastoma | Large cell medulloblastoma | Anaplastic medulloblastoma | Medulloblastoma with extensive nodularity | ||||||||||||||||||||||||||||||||||||
Genomic classification system | |||||||||||||||||||||||||||||||||||||||
Wnt subgroup | Sonic hedgehog(SHH) subgroup | Group 3 | Group 4 | ||||||||||||||||||||||||||||||||||||
References
- ↑ Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A; et al. (2007). "The 2007 WHO classification of tumours of the central nervous system". Acta Neuropathol. 114 (2): 97–109. doi:10.1007/s00401-007-0243-4. PMC 1929165. PMID 17618441.
- ↑ Leary SE, Olson JM (2012) The molecular classification of medulloblastoma: driving the next generation clinical trials. Curr Opin Pediatr 24 (1):33-9. DOI:10.1097/MOP.0b013e32834ec106 PMID: 22189395
- ↑ Medulloblastoma. Librepathology(2015) http://librepathology.org/wiki/index.php/Medulloblastoma Accessed on September, 28th 2015
- ↑ Medulloblastoma. radiopaedia(2015) http://radiopaedia.org/articles/medulloblastoma Accessed on September, 28th 2015