Glioma causes: Difference between revisions
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==Overview== | ==Overview== | ||
Common causes of glioma include genetic mutations. | Common causes of glioma include genetic mutations (''ERCC1'', ''[[ERCC2]]'', ''[[XRCC1]]'', ''MGMT'', ''IDH1'', ''[[IDH2]]'', ''[[p53]]'', ''[[EGFR]]'', ''[[TSC1]]'', ''[[TSC2]]'', ''[[RB1]]'', ''[[APC]]'', ''hMLH1'', ''hMSH2'', ''[[PMS2]]'', ''[[PTEN]]'', ''[[NF1]]'', and ''NF2'').<ref name=ddd>Pathology of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref><ref name="pmid16932614">{{cite journal| author=Schwartzbaum JA, Fisher JL, Aldape KD, Wrensch M| title=Epidemiology and molecular pathology of glioma. | journal=Nat Clin Pract Neurol | year= 2006 | volume= 2 | issue= 9 | pages= 494-503; quiz 1 p following 516 | pmid=16932614 | doi=10.1038/ncpneuro0289 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16932614 }} </ref> | ||
==Causes== | ==Causes== | ||
Common causes of glioma include genetic mutations. | *Common causes of glioma include genetic mutations. | ||
*The various genes include:<ref name=ddd>Pathology of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref><ref name="pmid16932614">{{cite journal| author=Schwartzbaum JA, Fisher JL, Aldape KD, Wrensch M| title=Epidemiology and molecular pathology of glioma. | journal=Nat Clin Pract Neurol | year= 2006 | volume= 2 | issue= 9 | pages= 494-503; quiz 1 p following 516 | pmid=16932614 | doi=10.1038/ncpneuro0289 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16932614 }} </ref> | |||
*''ERCC1'' | |||
*''[[ERCC2]]'' | |||
*''[[XRCC1]]'' | |||
*''MGMT'' | |||
*''IDH1'' | |||
*''[[IDH2]]'' | |||
*''[[p53]]'' | |||
*''[[EGFR]]'' | |||
*''[[TSC1]]'' | |||
*''[[TSC2]]'' | |||
*''[[RB1]]'' | |||
*''[[APC]]'' | |||
*''hMLH1'' | |||
*''hMSH2'' | |||
*''[[PMS2]]'' | |||
*''[[PTEN]]'' | |||
*''[[NF1]]'' | |||
*''NF2'' | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 13:43, 30 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Common causes of glioma include genetic mutations (ERCC1, ERCC2, XRCC1, MGMT, IDH1, IDH2, p53, EGFR, TSC1, TSC2, RB1, APC, hMLH1, hMSH2, PMS2, PTEN, NF1, and NF2).[1][2]
Causes
- Common causes of glioma include genetic mutations.
- The various genes include:[1][2]
- ERCC1
- ERCC2
- XRCC1
- MGMT
- IDH1
- IDH2
- p53
- EGFR
- TSC1
- TSC2
- RB1
- APC
- hMLH1
- hMSH2
- PMS2
- PTEN
- NF1
- NF2
References
- ↑ 1.0 1.1 Pathology of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
- ↑ 2.0 2.1 Schwartzbaum JA, Fisher JL, Aldape KD, Wrensch M (2006). "Epidemiology and molecular pathology of glioma". Nat Clin Pract Neurol. 2 (9): 494–503, quiz 1 p following 516. doi:10.1038/ncpneuro0289. PMID 16932614.