Medulloblastoma epidemiology and demographics: Difference between revisions
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* There is no racial predilection to medulloblastoma<ref name="pmid2010773">{{cite journal| author=Roberts RO, Lynch CF, Jones MP, Hart MN| title=Medulloblastoma: a population-based study of 532 cases. | journal=J Neuropathol Exp Neurol | year= 1991 | volume= 50 | issue= 2 | pages= 134-44 | pmid=2010773 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2010773 }} </ref> | |||
==References== | ==References== | ||
Revision as of 20:04, 30 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Epidemiology and Demographics
Prevalence
Incidence
- The overall age adjusted incidence rate of medulloblastoma is approximately 0.71 per 100,000 individuals in the United States.[1]
Age
- Medulloblastoma is the second most common brain tumor among the pediatric population, as it comprise 14.5% of newly diagnosed cases.[2]
- Medulloblastoma is considered a rare tumor among adults , as it compromise fewer than 2% of all brain tumors.
- The molecular subtgroup of medulloblastoma influence the age of presentation such as:[3]
- WNT medulloblastoma subgroup present among older children
- SHH medulloblastoma subgroup present among infants and adults
- Group 3 medulloblastoma present among younger children
- Group 4 medulloblastoma present among younger younger children
Gender
- The overall age adjusted incidence rate of medulloblastoma among male patients is approximately 0.84 per 100,000 individuals in the United States.[1]
- The overall age adjusted incidence rate of medulloblastoma among female patients is approximately 0.58 per 100,000 individuals in the United States.
- Males are more commonly affected with medulloblastoma than females. The male to female ratio is approximately 1.44 to 1.
Race
- There is no racial predilection to medulloblastoma[4]
References
- ↑ 1.0 1.1 McKean-Cowdin R, Razavi P, Barrington-Trimis J, Baldwin RT, Asgharzadeh S, Cockburn M; et al. (2013). "Trends in childhood brain tumor incidence, 1973-2009". J Neurooncol. 115 (2): 153–60. doi:10.1007/s11060-013-1212-5. PMC 4056769. PMID 23925828.
- ↑ Medulloblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Medulloblastoma Accessed on September, 28th 2015
- ↑ Leary SE, Olson JM (2012) The molecular classification of medulloblastoma: driving the next generation clinical trials. Curr Opin Pediatr 24 (1):33-9. DOI:10.1097/MOP.0b013e32834ec106 PMID: 22189395
- ↑ Roberts RO, Lynch CF, Jones MP, Hart MN (1991). "Medulloblastoma: a population-based study of 532 cases". J Neuropathol Exp Neurol. 50 (2): 134–44. PMID 2010773.