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Angiomyolipoma must be differentiated from [[retroperitoneal liposarcoma]], [[adrenal myelolipoma]], and [[renal cell carcinoma]].<ref name=pmid25517956>{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref><ref name=aaa> Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma</ref>
Angiomyolipoma must be differentiated from [[retroperitoneal liposarcoma]], [[adrenal myelolipoma]], and [[renal cell carcinoma]].<ref name=pmid25517956>{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref><ref name=aaa> Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma</ref>


==Differential Diagnosis==
==Differentiating Angiomyolipoma from other Diseases==
Angiomyolipoma must be differentiated from the following:<ref name=pmid25517956>{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref><ref name=aaa> Renal angiomyolipoma differentia diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma</ref>
Angiomyolipoma must be differentiated from the following:<ref name=pmid25517956>{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref><ref name=aaa> Renal angiomyolipoma differentia diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma</ref>
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Revision as of 20:09, 30 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

Angiomyolipoma must be differentiated from retroperitoneal liposarcoma, adrenal myelolipoma, and renal cell carcinoma.[1][2]

Differentiating Angiomyolipoma from other Diseases

Angiomyolipoma must be differentiated from the following:[1][2]

Differential diagnosis Characteristic features of the differential diagnosis
Retroperitoneal liposarcoma
  • Presence of a large vessel extending into the renal cortex suggestive of angiomyolipoma; liposarcoma is hypovascular
  • Renal parenchymal defect at the site of tumour contact favours exophytic angiomyolipoma- claw sign
  • Calcifications suggest liposarcoma

Renal cell carcinoma
  • May contain fat
  • Lipid necrosis
  • Osseous metaplasia
Oncocytoma
  • May contain fat
Wilm's tumor
  • May contain fat
Retroperitoneal sarcoma
Renal cell carcinoma
  • Sarcomatoid differentiation
Renal leiomyoma
  • Very rare
  • Desmin +ve
  • HMB-45 -ve
Perirenal fat entrapment
  • Renal junctional parenchymal defect
Adrenal myelolipoma
  • Fat in renal parenchyma

References

  1. ↑ 1.0 1.1 Patil, PA.; McKenney, JK.; Trpkov, K.; Hes, O.; Montironi, R.; Scarpelli, M.; Nesi, G.; Aron, M.; Sangoi, AR. (2014). "Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm". Am J Surg Pathol. doi:10.1097/PAS.0000000000000354. PMID 25517956. Unknown parameter |month= ignored (help)
  2. ↑ 2.0 2.1 Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma

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