Vulvar cancer natural history: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 1: | Line 1: | ||
{{CMG}} __NOTOC__ | {{CMG}}{{AE}}{{MD}} | ||
__NOTOC__ | |||
{{Vulvar cancer}} | {{Vulvar cancer}} | ||
==Overview== | ==Overview== | ||
==Natural history== | ==Natural history== | ||
* In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as lichen sclerosus, especially in older age group. | * In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as lichen sclerosus, especially in older age group. | ||
* Patient has early symptoms like ulcer on vulva, chronic puritius of the vulva, lichenification, and wart-like patches on vulva. | * Patient has early symptoms like ulcer on vulva, chronic puritius of the vulva, lichenification, and wart-like patches on vulva. | ||
* As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, dysuria and dysparunia. | * As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, dysuria and dysparunia. | ||
| Line 12: | Line 10: | ||
* The patient may present with dyspnea, cough with blood-stained sputum, persistent pain or discomfort in the chest, edema hands/feet, and inguinal lymphadenopathy. | * The patient may present with dyspnea, cough with blood-stained sputum, persistent pain or discomfort in the chest, edema hands/feet, and inguinal lymphadenopathy. | ||
* Once the cancer spreads to the other organs, it is most likely fatal. | * Once the cancer spreads to the other organs, it is most likely fatal. | ||
==Complications== | ==Complications== | ||
* [[Pelvic pain]] | * [[Pelvic pain]] | ||
* Fistula | * Fistula | ||
*[[Metastasis]] - usually in the liver and lungs but may occur in other sites | *[[Metastasis]] - usually in the liver and lungs but may occur in other sites | ||
==Prognosis== | ==Prognosis== | ||
The prognosis of vulvar cancer shows overall about a 75% [[five year survival rate]], but, of course, individually affected by many factors, notably stage and type of the lesion and age and general medical health. Five-year survival is down to about 20% when pelvic lymph nodes are involved but better than 90% for patients with stage I lesions. Thus early diagnosis is imperative. | The prognosis of vulvar cancer shows overall about a 75% [[five year survival rate]], but, of course, individually affected by many factors, notably stage and type of the lesion and age and general medical health. Five-year survival is down to about 20% when pelvic lymph nodes are involved but better than 90% for patients with stage I lesions. Thus early diagnosis is imperative. | ||
Revision as of 15:29, 1 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
|
Vulvar cancer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Vulvar cancer natural history On the Web |
|
American Roentgen Ray Society Images of Vulvar cancer natural history |
|
Risk calculators and risk factors for Vulvar cancer natural history |
Overview
Natural history
- In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as lichen sclerosus, especially in older age group.
- Patient has early symptoms like ulcer on vulva, chronic puritius of the vulva, lichenification, and wart-like patches on vulva.
- As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, dysuria and dysparunia.
- In advanced disease, metastases may be present in the abdomen, lungs.
- The patient may present with dyspnea, cough with blood-stained sputum, persistent pain or discomfort in the chest, edema hands/feet, and inguinal lymphadenopathy.
- Once the cancer spreads to the other organs, it is most likely fatal.
Complications
- Pelvic pain
- Fistula
- Metastasis - usually in the liver and lungs but may occur in other sites
Prognosis
The prognosis of vulvar cancer shows overall about a 75% five year survival rate, but, of course, individually affected by many factors, notably stage and type of the lesion and age and general medical health. Five-year survival is down to about 20% when pelvic lymph nodes are involved but better than 90% for patients with stage I lesions. Thus early diagnosis is imperative. Squamous cell carcinoma of the vulva survival [1]
| Stage | 5-year relative survival (%) |
| I | 93% |
| II | 79% |
| III | 53% |
| 1V | 29% |
References
- ↑ Survival statistics for vulvar cancer. Vulvar cancer. http://www.cancer.ca/en/cancer-information/cancer-type/vulvar/prognosis-and-survival/survival-statistics/?region=ns Accessed on October 1, 2015