Vulvar cancer natural history: Difference between revisions

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Revision as of 15:32, 1 October 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as lichen sclerosus, especially in older age group.
Patient has early symptoms like ulcer on vulva, chronic puritius of the vulva, lichenification, and wart-like patches on vulva.
As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, dysuria and dysparunia.
In advanced disease, metastases may be present in the abdomen, lungs.
The patient may present with dyspnea, cough with blood-stained sputum, persistent pain or discomfort in the chest, edema hands/feet, and inguinal lymphadenopathy.
Once the cancer spreads to the other organs, it is most likely fatal.

Squamous cell carcinoma of the vulva survival ^[1]

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 *[[Metastasis]] - usually in the liver and lungs but may occur in other sites
 ==Prognosis==
-The prognosis of vulvar cancer shows overall about a 75% [[five year survival rate]], but, of course, individually affected by many factors, notably stage and type of the lesion and age and general medical health. Five-year survival is down to about 20% when pelvic lymph nodes are involved but better than 90% for patients with stage I lesions. Thus early diagnosis is imperative.
 Squamous cell carcinoma of the vulva survival <ref> Survival statistics for vulvar cancer. Vulvar cancer. http://www.cancer.ca/en/cancer-information/cancer-type/vulvar/prognosis-and-survival/survival-statistics/?region=ns Accessed on October 1, 2015</ref>
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