Vulvar cancer natural history: Difference between revisions
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{{Vulvar cancer}} | {{Vulvar cancer}} | ||
==Overview== | ==Overview== | ||
If left untreated, patients with vulvar cancer may progress to develop [[ulcer]] on vulva or wart-like patches on vulva, chronic [[pruritus]] of the vulva and lichenification. Common complications of vulvar cancer include fistula and metastasis. Prognosis is generally good, and the 5 year survival rate of patients with vulvar cancer is approximately 71.2%. | If left untreated, patients with vulvar cancer may progress to develop [[ulcer]] on vulva or wart-like patches on vulva, chronic [[pruritus]] of the vulva and lichenification. Common complications of vulvar cancer include fistula and [[metastasis]]. Prognosis is generally good, and the 5 year survival rate of patients with vulvar cancer is approximately 71.2%. | ||
==Natural history== | ==Natural history== | ||
* In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as [[lichen sclerosus]], especially in older age group. | * In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as [[lichen sclerosus]], especially in older age group. | ||
* Patient has early symptoms like ulcer on vulva, chronic [[pruritus]] of the vulva, lichenification, and wart-like patches on [[vulva]]. | * Patient has early symptoms like ulcer on vulva, chronic [[pruritus]] of the vulva, lichenification, and wart-like patches on [[vulva]]. | ||
* As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, [[dysuria]] and [[ | * As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, [[dysuria]] and [[dyspareunia]]. | ||
* In advanced disease, [[metastasis|metastases]] may be present in the [[abdomen]], [[lung]]s. | * In advanced disease, [[metastasis|metastases]] may be present in the [[abdomen]], [[lung]]s. | ||
* The patient may present with [[dyspnea]], [[cough]] with blood-stained sputum, persistent pain or discomfort in the chest, [[edema]] hands/feet, and [[inguinal lymphadenopathy]]. | * The patient may present with [[dyspnea]], [[cough]] with blood-stained sputum, persistent pain or discomfort in the chest, [[edema]] hands/feet, and [[inguinal lymphadenopathy]]. | ||
Revision as of 20:10, 1 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
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Risk calculators and risk factors for Vulvar cancer natural history |
Overview
If left untreated, patients with vulvar cancer may progress to develop ulcer on vulva or wart-like patches on vulva, chronic pruritus of the vulva and lichenification. Common complications of vulvar cancer include fistula and metastasis. Prognosis is generally good, and the 5 year survival rate of patients with vulvar cancer is approximately 71.2%.
Natural history
- In younger age group, HPV infection can be the cause of vulvar cancer. Vulvar cancer may be associated vulvar dermatoses, such as lichen sclerosus, especially in older age group.
- Patient has early symptoms like ulcer on vulva, chronic pruritus of the vulva, lichenification, and wart-like patches on vulva.
- As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, dysuria and dyspareunia.
- In advanced disease, metastases may be present in the abdomen, lungs.
- The patient may present with dyspnea, cough with blood-stained sputum, persistent pain or discomfort in the chest, edema hands/feet, and inguinal lymphadenopathy.
- Once the cancer spreads to the other organs, it is most likely fatal.
Complications
- Pelvic pain
- Fistula
- Metastasis - usually in the liver and lungs but may occur in other sites
Prognosis
Vulvar cancer is associated with a 5 year survival rate of 71.2%. Following is the table for squamous cell carcinoma of the vulva survival [1]
| Stage | 5-year relative survival (%) |
| I | 93% |
| II | 79% |
| III | 53% |
| 1V | 29% |
References
- ↑ Survival statistics for vulvar cancer. Vulvar cancer. http://www.cancer.ca/en/cancer-information/cancer-type/vulvar/prognosis-and-survival/survival-statistics/?region=ns Accessed on October 1, 2015