Brain abscess natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
Over the past 50 years, the prognosis for patients with brain abscesses has improved significantly. These advances include further knowledge of cranial imaging techniques, antimicrobial treatment regimens, and the introduction of minimally invasive neurosurgical procedures. While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. 70% of patients with brain abscesses have a good outcome, rarely with minimal neurological [[sequelae, complications and prognosis|sequelae]] <ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref>. | |||
==References== | ==References== | ||
Revision as of 18:25, 2 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Complications
Mortality is currently quoted to range from 0 – 24%.
- Poor prognostic indicators include:
- Intraventricular rupture:
- 80% mortality rate, often treated with open drainage and debridement f/b ventriculostomy catheter for drainage and intrathecal abx
- Mental status and neurologic function at time of Dx:
- The most common sequellae is seizures, which develop in 35 – 70% of patients.
Prognosis
Over the past 50 years, the prognosis for patients with brain abscesses has improved significantly. These advances include further knowledge of cranial imaging techniques, antimicrobial treatment regimens, and the introduction of minimally invasive neurosurgical procedures. While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. 70% of patients with brain abscesses have a good outcome, rarely with minimal neurological sequelae [1].
References
- ↑ Brouwer MC, Tunkel AR, McKhann GM, van de Beek D (2014). "Brain abscess". N Engl J Med. 371 (5): 447–56. doi:10.1056/NEJMra1301635. PMID 25075836.