Medulloblastoma staging: Difference between revisions
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==Overview== | ==Overview== | ||
The staging of medulloblastoma is based on the modified Chang's staging system. Medulloblastoma | The staging of medulloblastoma is based on the modified Chang's staging system. Medulloblastoma patients are risk stratified into either standard risk group or high risk group based on the [[tumor]] stage, patient's age, and the extent of any previous surgical resection.<ref name="pmid597384">{{cite journal| author=Harisiadis L, Chang CH| title=Medulloblastoma in children: a correlation between staging and results of treatment. | journal=Int J Radiat Oncol Biol Phys | year= 1977 | volume= 2 | issue= 9-10 | pages= 833-41 | pmid=597384 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=597384 }} </ref><ref name="b">Medulloblastoma staging. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 282015)</ref> | ||
==Modified Chang's Staging of Medulloblastoma== | ==Modified Chang's Staging of Medulloblastoma== | ||
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==Risk Stratification== | ==Risk Stratification== | ||
* Medulloblastoma | * Medulloblastoma patients are risk stratified into either a standard risk group or a high risk group based on the [[tumor]] stage, patient's age, and the extent of any previous surgical resection.<ref name="pmid23245832">{{cite journal| author=Bartlett F, Kortmann R, Saran F| title=Medulloblastoma. | journal=Clin Oncol (R Coll Radiol) | year= 2013 | volume= 25 | issue= 1 | pages= 36-45 | pmid=23245832 | doi=10.1016/j.clon.2012.09.008 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23245832 }} </ref> | ||
* Risk stratification determines the protocol of management used for medulloblastoma patients. | * Risk stratification determines the protocol of management used for medulloblastoma patients. | ||
* The table below demonstrates the risk stratification for medulloblastoma patients:<ref name="pmid23245832">{{cite journal| author=Bartlett F, Kortmann R, Saran F| title=Medulloblastoma. | journal=Clin Oncol (R Coll Radiol) | year= 2013 | volume= 25 | issue= 1 | pages= 36-45 | pmid=23245832 | doi=10.1016/j.clon.2012.09.008 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23245832 }} </ref><ref name="b">Medulloblastoma staging. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, | * The table below demonstrates the risk stratification for medulloblastoma patients:<ref name="pmid23245832">{{cite journal| author=Bartlett F, Kortmann R, Saran F| title=Medulloblastoma. | journal=Clin Oncol (R Coll Radiol) | year= 2013 | volume= 25 | issue= 1 | pages= 36-45 | pmid=23245832 | doi=10.1016/j.clon.2012.09.008 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23245832 }} </ref><ref name="b">Medulloblastoma staging. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 282015)</ref> | ||
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Revision as of 19:54, 3 October 2015
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Medulloblastoma Microchapters |
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Medulloblastoma staging On the Web |
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American Roentgen Ray Society Images of Medulloblastoma staging |
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Risk calculators and risk factors for Medulloblastoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
The staging of medulloblastoma is based on the modified Chang's staging system. Medulloblastoma patients are risk stratified into either standard risk group or high risk group based on the tumor stage, patient's age, and the extent of any previous surgical resection.[1][2]
Modified Chang's Staging of Medulloblastoma
The staging of medulloblastoma is based on the modified Chang staging system.[1]
T: Primary Tumor
| T | Description |
| TX | Primary tumor cannot be assessed |
| T0 | There is no evidence of primary tumor |
| T1 | Tumor size <3 cm in diameter |
| T2 | Tumor size ≥3 cm in diameter with no evidence of extension |
| T3a | Tumor size >3 cm in diameter with extension into aqueduct of Sylvius or foramen of Luschka |
| T3b | Tumor size >3 cm in diameter with definite spread into the brain stem |
| T4 | Tumor size >3 cm in diameter with extension past aqueduct of Sylvius or down past foramen magnum |
M: Distant Metastasis
| M | Description |
| M0 | No evidence of metastasis |
| M1 | Microscopic tumor cells present in the cerebrospinal fluid |
| M2 | Gross nodular seeding present intracranially beyond the primary tumor site |
| M3 | Gross nodular seeding present in the spinal subarachnoid space |
| M4 | Metastasis present outside the cerebrospinal axis |
Risk Stratification
- Medulloblastoma patients are risk stratified into either a standard risk group or a high risk group based on the tumor stage, patient's age, and the extent of any previous surgical resection.[3]
- Risk stratification determines the protocol of management used for medulloblastoma patients.
- The table below demonstrates the risk stratification for medulloblastoma patients:[3][2]
| Parameters | Standard Risk Group | High Risk Group |
|---|---|---|
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Age |
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Extent of previous surgical resection |
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Tumor stage |
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References
- ↑ 1.0 1.1 Harisiadis L, Chang CH (1977). "Medulloblastoma in children: a correlation between staging and results of treatment". Int J Radiat Oncol Biol Phys. 2 (9–10): 833–41. PMID 597384.
- ↑ 2.0 2.1 Medulloblastoma staging. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 282015)
- ↑ 3.0 3.1 Bartlett F, Kortmann R, Saran F (2013). "Medulloblastoma". Clin Oncol (R Coll Radiol). 25 (1): 36–45. doi:10.1016/j.clon.2012.09.008. PMID 23245832.