Optic nerve glioma differential diagnosis: Difference between revisions
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Optic nerve glioma must be differentiated from other diseases that cause optic nerve enlargement and from [[tumors]] located at optic chiasm, such as optic nerve [[meningioma]], orbital pseudotumor, [[optic]] [[neuritis]], orbital [[lymphomas]], [[metastasis]], [[fibrous]] [[dysplasia]], paranasal [[mucocele]], [[rhabdomyosarcoma]], [[neurofibromatosis]], perioptic [[haemorrhage]], Erdheim-Chester disease, [[juvenile xanthogranuloma]], medulloepithelioma, [[retinoblastoma]], Krabbe disease, optic nerve and chiasm glioma such as [[germinoma]] and [[sarcoidosis]], and optic chiasm glioma extending into the hypothalamus such as [[pituitary adenoma]], [[craniopharyngioma]], [[malignant]] [[astrocytoma]], dermoid cyst, [[chordoma]], colloid cyst, [[histiocytosis X]], [[tuberculous granuloma]], and hemangloendothelioma.<ref name="radio"> Optic nerve glioma. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-glioma Accessed on October 2 2015</ref> | Optic nerve glioma must be differentiated from other diseases that cause optic nerve enlargement and from [[tumors]] located at optic chiasm, such as optic nerve [[meningioma]], orbital pseudotumor, [[optic]] [[neuritis]], orbital [[lymphomas]], [[metastasis]], [[fibrous]] [[dysplasia]], paranasal [[mucocele]], [[rhabdomyosarcoma]], [[neurofibromatosis]], perioptic [[haemorrhage]], Erdheim-Chester disease, [[juvenile xanthogranuloma]], medulloepithelioma, [[retinoblastoma]], Krabbe disease, optic nerve and chiasm glioma such as [[germinoma]] and [[sarcoidosis]], and optic chiasm glioma extending into the hypothalamus such as [[pituitary adenoma]], [[craniopharyngioma]], [[malignant]] [[astrocytoma]], dermoid cyst, [[chordoma]], colloid cyst, [[histiocytosis X]], [[tuberculous granuloma]], and hemangloendothelioma.<ref name="radio"> Optic nerve glioma. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-glioma Accessed on October 2 2015</ref> | ||
==Differentiating Optic nerve glioma from other diseases== | ==Differentiating Optic nerve glioma from other diseases== | ||
The main differential is that of optic nerve meningioma however the potential list is much longer including most causes of optic nerve enlargement.<ref name=" | The main differential is that of optic nerve meningioma however the potential list is much longer including most causes of optic nerve enlargement.<ref name="radio1"> Optic nerve enlargement. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-enlargement Accessed on October 2 2015</ref> Absence of calcification can be used to differentiate optic nerve glioma from [[optic nerve sheath meningioma]]. Additionally, when the bulk of the tumor is located at the chiasm, the differential should include pituitary region masses. The differential diagnosis of optic nerve glioma include: | ||
*Optic nerve [[meningioma]] | *Optic nerve [[meningioma]] | ||
*Orbital pseudotumor | *Orbital pseudotumor | ||
Revision as of 01:26, 6 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Optic nerve glioma must be differentiated from other diseases that cause optic nerve enlargement and from tumors located at optic chiasm, such as optic nerve meningioma, orbital pseudotumor, optic neuritis, orbital lymphomas, metastasis, fibrous dysplasia, paranasal mucocele, rhabdomyosarcoma, neurofibromatosis, perioptic haemorrhage, Erdheim-Chester disease, juvenile xanthogranuloma, medulloepithelioma, retinoblastoma, Krabbe disease, optic nerve and chiasm glioma such as germinoma and sarcoidosis, and optic chiasm glioma extending into the hypothalamus such as pituitary adenoma, craniopharyngioma, malignant astrocytoma, dermoid cyst, chordoma, colloid cyst, histiocytosis X, tuberculous granuloma, and hemangloendothelioma.[1]
Differentiating Optic nerve glioma from other diseases
The main differential is that of optic nerve meningioma however the potential list is much longer including most causes of optic nerve enlargement.[2] Absence of calcification can be used to differentiate optic nerve glioma from optic nerve sheath meningioma. Additionally, when the bulk of the tumor is located at the chiasm, the differential should include pituitary region masses. The differential diagnosis of optic nerve glioma include:
- Optic nerve meningioma
- Orbital pseudotumor
- Optic neuritis
- Orbital lymphoma
- Metastases(Neuroblastoma, Leukemia, Ewing's sarcoma)
- Fibrous dysplasia
- Paranasal mucocele
- Hemangioma
- Rhabdomyosarcoma
- Neurofibromatosis
- Perioptic haemorrhage
- Erdheim-Chester disease
- Juvenile xanthogranuloma
- Medulloepithelioma
- Retinoblastoma
- Krabbe disease
- Optic nerve and chiasm glioma:
- Optic chiasm glioma extending into the hypothalamus:
- Pituitary adenoma
- Craniopharyngioma
- Malignant astrocytoma
- Dermoid cyst
- Chordoma
- Colloid cyst
- Histiocytosis X
- Tuberculous granuloma
- Hemangloendothelioma
References
- ↑ Optic nerve glioma. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-glioma Accessed on October 2 2015
- ↑ Optic nerve enlargement. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-enlargement Accessed on October 2 2015