Chronic myelogenous leukemia historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
In the 1840s, the first cases of chronic myelogenous leukemia ([[splenomegaly]] with high [[leukocyte]] count) was reported in France, Germany, and Scotland. In 1960, the association of [[Philadelphia chromosome]] with the pathogenesis of chronic myelogenous leukemia was discovered. In 1973, (9;22) translocation was first discovered. | In the 1840s, the first cases of chronic myelogenous leukemia ([[splenomegaly]] with high [[leukocyte]] count) was reported in France, Germany, and Scotland. In 1960, the association of [[Philadelphia chromosome]] with the pathogenesis of chronic myelogenous leukemia was discovered. In 1973, (9;22) translocation was first discovered.<ref name="Goldman2010">{{cite journal|last1=Goldman|first1=John M.|title=Chronic Myeloid Leukemia: A Historical Perspective|journal=Seminars in Hematology|volume=47|issue=4|year=2010|pages=302–311|issn=00371963|doi=10.1053/j.seminhematol.2010.07.001}}</ref> | ||
==Historical Perspective== | ==Historical Perspective== | ||
Important dates in chronic myelogenous leukemia: | Important dates in chronic myelogenous leukemia:<ref name="Goldman2010">{{cite journal|last1=Goldman|first1=John M.|title=Chronic Myeloid Leukemia: A Historical Perspective|journal=Seminars in Hematology|volume=47|issue=4|year=2010|pages=302–311|issn=00371963|doi=10.1053/j.seminhematol.2010.07.001}}</ref> | ||
* In the 1840s, the first cases of Chronic myelogenous leukemia was reported | * In the 1840s, the first cases of Chronic myelogenous leukemia was reported | ||
* In 1960, [[Philadelphia chromosome]] was first discovered. | * In 1960, [[Philadelphia chromosome]] was first discovered. | ||
Revision as of 15:27, 6 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
In the 1840s, the first cases of chronic myelogenous leukemia (splenomegaly with high leukocyte count) was reported in France, Germany, and Scotland. In 1960, the association of Philadelphia chromosome with the pathogenesis of chronic myelogenous leukemia was discovered. In 1973, (9;22) translocation was first discovered.[1]
Historical Perspective
Important dates in chronic myelogenous leukemia:[1]
- In the 1840s, the first cases of Chronic myelogenous leukemia was reported
- In 1960, Philadelphia chromosome was first discovered.
- In 1973, (9;22) translocation was first discovered.
- In 1985, the BCR-ABL transcript was first discovered.