Trichomoniasis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
===Antimicrobial Regimen=== | ===Antimicrobial Regimen=== | ||
:* 1. '''T. vaginalis infection in adults''' <ref>{{cite web | title =trichomoniasis | url = http://www.cdc.gov/std/tg2015/trichomoniasis.htm }}</ref> | :* 1. '''T. vaginalis infection in adults'''<ref>{{cite web | title =trichomoniasis | url = http://www.cdc.gov/std/tg2015/trichomoniasis.htm }}</ref> | ||
::* Preferred regimen (1): [[Metronidazole]] 2 g PO in a single dose | ::* Preferred regimen (1): [[Metronidazole]] 2 g PO in a single dose | ||
::* Preferred regimen (2): [[Tinidazole]] 2 g PO in a single dose | ::* Preferred regimen (2): [[Tinidazole]] 2 g PO in a single dose | ||
| Line 14: | Line 14: | ||
:* 2. '''T. vaginalis infection in pregnant and lactating Women''' | :* 2. '''T. vaginalis infection in pregnant and lactating Women''' | ||
::* 2.1 '''Pregnant women''' | ::* 2.1 '''Pregnant women''' | ||
:::* Preferred regimen: [[Metronidazole]] 2 g PO in a single dose | :::* Preferred regimen: [[Metronidazole]] 2 g PO in a single dose | ||
::* 2.2 '''Post-partum and Breastfeeding''' | ::* 2.2 '''Post-partum and Breastfeeding''' | ||
:::* Preferred regimen (1): [[Metronidazole]] 2 g PO in a single dose | :::* Preferred regimen (1): [[Metronidazole]] 2 g PO in a single dose | ||
:::* Preferred regimen (2): [[Tinidazole]] 2 g PO in a single dose | :::* Preferred regimen (2): [[Tinidazole]] 2 g PO in a single dose | ||
:::* Note (1): Do not breastfeed for 12-24 hrs following [[Metronidazole]] and 72 hrs following [[Tinidazole]] | :::* Note (1): Do not breastfeed for 12-24 hrs following [[Metronidazole]] and 72 hrs following [[Tinidazole]] | ||
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::* Preferred regimen: [[Metronidazole]] 500 mg PO bid for 7 days | ::* Preferred regimen: [[Metronidazole]] 500 mg PO bid for 7 days | ||
:* 4. '''Persistent or recurrent trichomoniasis''' | :* 4. '''Persistent or recurrent trichomoniasis''' | ||
::* 4.1 '''Treatment failure''' | ::* 4.1 '''Treatment failure, first-time''' | ||
:::* Preferred regimen: [[Metronidazole]] 500 mg PO bid for 7 days | :::* Preferred regimen: [[Metronidazole]] 500 mg PO bid for 7 days | ||
::* 4.2 '''Treatment failure | ::* 4.2 '''Treatment failure, second-time''' | ||
:::* Preferred regimen (1): [[Metronidazole]] 2 g PO for 7 days | :::* Preferred regimen (1): [[Metronidazole]] 2 g PO for 7 days | ||
:::* Preferred regimen (2): [[Tinidazole]] 2 g PO for 7 days | :::* Preferred regimen (2): [[Tinidazole]] 2 g PO for 7 days | ||
Revision as of 15:29, 6 October 2015
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Trichomoniasis Microchapters |
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Trichomoniasis medical therapy On the Web |
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American Roentgen Ray Society Images of Trichomoniasis medical therapy |
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Risk calculators and risk factors for Trichomoniasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Antimicrobial therapy is indicated in trichomoniasis. Most cases of trichomoniasis can be treated with Metronidazole. The symptoms of trichomoniasis in infected men may disappear within a few weeks without treatment. However, an infected man, even a man who has never had symptoms or whose symptoms have stopped, can continue to infect or re-infect a female partner until he has been treated. Therefore, both partners should be treated at the same time to eliminate the parasite. Individuals being treated for trichomoniasis should avoid sex until both they and their sex partners complete treatment and have no symptoms. Following successful treatment, individuals may still be susceptible to re-infection.
Medical Therapy
Antimicrobial Regimen
- 1. T. vaginalis infection in adults[1]
- Preferred regimen (1): Metronidazole 2 g PO in a single dose
- Preferred regimen (2): Tinidazole 2 g PO in a single dose
- Alternative regimen: Metronidazole 500 mg PO bid for 7 days
- 2. T. vaginalis infection in pregnant and lactating Women
- 2.1 Pregnant women
- Preferred regimen: Metronidazole 2 g PO in a single dose
- 2.2 Post-partum and Breastfeeding
- Preferred regimen (1): Metronidazole 2 g PO in a single dose
- Preferred regimen (2): Tinidazole 2 g PO in a single dose
- Note (1): Do not breastfeed for 12-24 hrs following Metronidazole and 72 hrs following Tinidazole
- Note (2): Symptomatic pregnant women, regardless of pregnancy stage, should be tested and considered for treatment. Pregnant women should be advised of the risk and benefits to treatment as infection (definitely) and treatment (possibly)
- Note (3): Pregnant women with HIV who are treated for T. vaginalis infection should be retested 3 months after treatment.
- 3. T. vaginalis infection in patients with HIV
- Preferred regimen: Metronidazole 500 mg PO bid for 7 days
- 4. Persistent or recurrent trichomoniasis
- 4.1 Treatment failure, first-time
- Preferred regimen: Metronidazole 500 mg PO bid for 7 days
- 4.2 Treatment failure, second-time
- Preferred regimen (1): Metronidazole 2 g PO for 7 days
- Preferred regimen (2): Tinidazole 2 g PO for 7 days
- 4.3 Nitroimidazole-resistant cases
- Preferred regimen: Tinidazole 2-3 g PO for 14 days