Anaplastic large cell lymphoma medical therapy: Difference between revisions
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The predominant therapy for anaplastic lymphoma is [[chemotherapy]]. Adjunctive [[radiotherapy]], [[stem cell transplantation]] and [[surgery]] may be required. The optimal therapy for anaplastic large cell lymphoma depends on the type and extent of anaplastic large cell lymphoma. | The predominant therapy for anaplastic lymphoma is [[chemotherapy]]. Adjunctive [[radiotherapy]], [[stem cell transplantation]] and [[surgery]] may be required. The optimal therapy for anaplastic large cell lymphoma depends on the type and extent of anaplastic large cell lymphoma. | ||
==Medical Therapy== | ==Medical Therapy== | ||
* The optimal therapy for anaplastic large cell lymphoma depends on: <ref name= canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref> | * The optimal therapy for anaplastic large cell lymphoma depends on:<ref name= canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref> | ||
:* Type of anaplastic large cell lymphoma | :* Type of anaplastic large cell lymphoma | ||
:* Extent of anaplastic large cell lymphoma | :* Extent of anaplastic large cell lymphoma | ||
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|+ '''Treatment for anaplastic large cell lymphoma<ref= | |+ '''Treatment for anaplastic large cell lymphoma<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>''' | ||
! style="background: #4479BA;; color:#FFF;" | Type | ! style="background: #4479BA;; color:#FFF;" | Type | ||
! style="background: #4479BA;; color:#FFF;" | Chemotherapy | ! style="background: #4479BA;; color:#FFF;" | Chemotherapy | ||
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===Chemotherapy<ref= | ===Chemotherapy<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>=== | ||
* Anaplastic large cell lymphoma usually responds well to chemotherapy, so it often has a good prognosis | * Anaplastic large cell lymphoma usually responds well to chemotherapy, so it often has a good prognosis | ||
* It is treated with the same combinations of chemotherapy drugs used to treat other aggressive lymphomas | * It is treated with the same combinations of chemotherapy drugs used to treat other aggressive lymphomas | ||
* Drug Regimen: (CHOP) [[Cyclophosphamide]] {{and}} [[Doxorubicin]] {{and}} [[Vincristine]] {{and}} [[Prednisone]] | * Drug Regimen: (CHOP) [[Cyclophosphamide]] {{and}} [[Doxorubicin]] {{and}} [[Vincristine]] {{and}} [[Prednisone]] | ||
===Radiation therapy<ref= | ===Radiation therapy<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>=== | ||
* Radiation therapy is most often given after chemotherapy | * Radiation therapy is most often given after chemotherapy | ||
* External beam radiation therapy may be used | * External beam radiation therapy may be used | ||
:* When the lymphoma cells are only in one area of the lymph nodes (stage I primary systemic anaplastic large cell lymphoma) | :* When the lymphoma cells are only in one area of the lymph nodes (stage I primary systemic anaplastic large cell lymphoma) | ||
:* For localized skin lesions in primary cutaneous anaplastic large cell lymphoma | :* For localized skin lesions in primary cutaneous anaplastic large cell lymphoma | ||
===Stem cell transplant<ref= | ===Stem cell transplant<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>=== | ||
* A stem cell transplant may be offered to some people with anaplastic large cell lymphoma who relapse after initial treatment | * A stem cell transplant may be offered to some people with anaplastic large cell lymphoma who relapse after initial treatment | ||
==References== | ==References== | ||
Revision as of 16:19, 6 October 2015
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Anaplastic large cell lymphoma Microchapters |
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Differentiating Anaplastic large cell lymphoma from other Diseases |
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Anaplastic large cell lymphoma medical therapy On the Web |
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Risk calculators and risk factors for Anaplastic large cell lymphoma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
The predominant therapy for anaplastic lymphoma is chemotherapy. Adjunctive radiotherapy, stem cell transplantation and surgery may be required. The optimal therapy for anaplastic large cell lymphoma depends on the type and extent of anaplastic large cell lymphoma.
Medical Therapy
- The optimal therapy for anaplastic large cell lymphoma depends on:[1]
- Type of anaplastic large cell lymphoma
- Extent of anaplastic large cell lymphoma
| Type | Chemotherapy | Radiotherapy | Stem cell transplant | Surgery |
|---|---|---|---|---|
| Primary cutaneous anaplastic large cell lymphoma |
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| Primary systemic anaplastic large cell lymphoma |
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Chemotherapy<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>
- Anaplastic large cell lymphoma usually responds well to chemotherapy, so it often has a good prognosis
- It is treated with the same combinations of chemotherapy drugs used to treat other aggressive lymphomas
- Drug Regimen: (CHOP) Cyclophosphamide AND Doxorubicin AND Vincristine AND Prednisone
Radiation therapy<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>
- Radiation therapy is most often given after chemotherapy
- External beam radiation therapy may be used
- When the lymphoma cells are only in one area of the lymph nodes (stage I primary systemic anaplastic large cell lymphoma)
- For localized skin lesions in primary cutaneous anaplastic large cell lymphoma
Stem cell transplant<ref=canadiancancer> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015</ref>
- A stem cell transplant may be offered to some people with anaplastic large cell lymphoma who relapse after initial treatment
References
- ↑ Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 6,2015