Differentiating Thyroid adenoma from other Diseases: Difference between revisions
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==Differentiating Thyroid adenoma from other Diseases== | ==Differentiating Thyroid adenoma from other Diseases== | ||
A thyroid adenoma is distinguished from a [[multinodular goiter]] of the thyroid in that an adenoma is typically solitary, and is a [[neoplasm]] resulting from a genetic [[mutation]] (or other genetic abnormality) in a single precursor cell.<ref name="robbins">{{cite book |author=Ramzi Cotran, Vinay Kumar, Tucker Collins |title=Robbins Pathologic Basis of Disease, 6th Edition |year=1999 |publisher=W.B. Saunders |isbn=0-7216-7335-X |pages=}}</ref> In contrast, a multinodular goiter is usually thought to result from a [[hyperplasia|hyperplastic]] response of the entire thyroid gland to a stimulus, such as [[iodine deficiency]]. | A thyroid adenoma is distinguished from a [[multinodular goiter]] of the thyroid in that an adenoma is typically solitary, and is a [[neoplasm]] resulting from a genetic [[mutation]] (or other genetic abnormality) in a single precursor cell.<ref name="robbins">{{cite book |author=Ramzi Cotran, Vinay Kumar, Tucker Collins |title=Robbins Pathologic Basis of Disease, 6th Edition |year=1999 |publisher=W.B. Saunders |isbn=0-7216-7335-X |pages=}}</ref> In contrast, a multinodular goiter is usually thought to result from a [[hyperplasia|hyperplastic]] response of the entire thyroid gland to a stimulus, such as [[iodine deficiency]]. | ||
Careful [[pathology|pathological]] examination may be necessary to distinguish a thyroid adenoma from a minimally invasive follicular thyroid carcinoma. | Careful [[pathology|pathological]] examination may be necessary to distinguish a thyroid adenoma from a minimally invasive follicular thyroid carcinoma. | ||
The table below summarizes the findings that differentiate [[thyroid adenoma]] from other conditions that cause neck swelling. | |||
==References== | ==References== | ||
Revision as of 02:36, 7 October 2015
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Overview
Differentiating Thyroid adenoma from other Diseases
A thyroid adenoma is distinguished from a multinodular goiter of the thyroid in that an adenoma is typically solitary, and is a neoplasm resulting from a genetic mutation (or other genetic abnormality) in a single precursor cell.[1] In contrast, a multinodular goiter is usually thought to result from a hyperplastic response of the entire thyroid gland to a stimulus, such as iodine deficiency. Careful pathological examination may be necessary to distinguish a thyroid adenoma from a minimally invasive follicular thyroid carcinoma. The table below summarizes the findings that differentiate thyroid adenoma from other conditions that cause neck swelling.
References
- ↑ Ramzi Cotran, Vinay Kumar, Tucker Collins (1999). Robbins Pathologic Basis of Disease, 6th Edition. W.B. Saunders. ISBN 0-7216-7335-X.