Chronic myelogenous leukemia staging: Difference between revisions
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{{Chronic myelogenous leukemia}} | {{Chronic myelogenous leukemia}} | ||
{{CMG}} {{AE}} {{MJK}} | |||
==Overview== | |||
Chronic myelogenous leukemia may be classified according to the clinical characteristics and laboratory findings into three subtypes: chronic phase, accelerated phase, and blast crisis. | |||
==Classification== | |||
Chronic myelogenous leukemia is often divided into three phases based on clinical characteristics and laboratory findings.<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/staging/?region=ab</ref> | |||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Phases}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Associations}} | |||
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Chronic phase | |||
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*Most patients are diagnosed in this phase | |||
*Less than 10% of cells in the blood and bone marrow are blasts | |||
*Usually asymptomatic or mild symptoms my present | |||
*Progress slowly | |||
*Respond well to treatment | |||
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Accelerated phase | |||
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*10-20% of cells in the blood and bone marrow are blasts | |||
*Cells show more damage to their DNA and grow faster | |||
*Cells have often developed new changes in addition to the Philadelphia chromosome | |||
*Usually symptomatic | |||
*Poor response to treatment | |||
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Blast or acute phase | |||
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*Disease acts more like an acute leukemia | |||
*30% of cells in blood and bone marrow are blast | |||
*Blast cells often spread to tissues and organs outside the bone marrow | |||
*Blast crisis may occur | |||
:*The accelerated phase can change quickly into the blast phase with symptoms of fever, malaise, and [[splenomegaly]] | |||
*Usually symptomatic | |||
*Bleeding and infections are common | |||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] |
Revision as of 13:15, 8 October 2015
Chronic myelogenous leukemia Microchapters |
Differentiating Chronic myelogenous leukemia from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Chronic myelogenous leukemia staging On the Web |
American Roentgen Ray Society Images of Chronic myelogenous leukemia staging |
Directions to Hospitals Treating Chronic myelogenous leukemia |
Risk calculators and risk factors for Chronic myelogenous leukemia staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Chronic myelogenous leukemia may be classified according to the clinical characteristics and laboratory findings into three subtypes: chronic phase, accelerated phase, and blast crisis.
Classification
Chronic myelogenous leukemia is often divided into three phases based on clinical characteristics and laboratory findings.[1]
Phases | Associations |
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Chronic phase |
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Accelerated phase |
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Blast or acute phase |
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References
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/staging/?region=ab