Ependymoma medical therapy: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
== | ==Chemotherapy== | ||
* | *There is no evidence to date that adjuvant chemotherapy, including the use of myeloablative chemotherapy,<ref name="pmid34-40">{{cite journal| author=Warth J, Desforges JF| title=Determinants of intracellular pH in the erythrocyte. | journal=Br J Haematol | year= 1975 | volume= 29 | issue= 3 | pages= 369-72 | pmid=34-40 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=34 }} </ref> improves the outcome for patients with totally resected, nondisseminated ependymoma.<ref name="pmid1293-301">{{cite journal| author=Kozlova MV| title=[Differences in the responses of taste receptors to organic and inorganic acids with changes in the concentration of bicarbonate in the solution]. | journal=Fiziol Zh SSSR Im I M Sechenova | year= 1975 | volume= 61 | issue= 7 | pages= 1000-7 | pmid=1293-301 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1293 }} </ref> | ||
*current treatment approaches do not include chemotherapy as a standard component of primary therapy for children with newly diagnosed ependymomas that are completely resected. | |||
==Radiation Therapy== | ==Radiation Therapy== | ||
*Radiation therapy consisting of 54 Gy to 55.8 Gy is recommended for children aged 3 years and older who are diagnosed with well-differentiated ependymomas.<ref name="pmid583-90">{{cite journal| author=Diewitz M| title=[Coronary heart disease and its differential treatment]. | journal=Med Welt | year= 1975 | volume= 26 | issue= 43 | pages= 1980-8 | pmid=583-90 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=583 }} </ref> | *Radiation therapy consisting of 54 Gy to 55.8 Gy is recommended for children aged 3 years and older who are diagnosed with well-differentiated ependymomas.<ref name="pmid583-90">{{cite journal| author=Diewitz M| title=[Coronary heart disease and its differential treatment]. | journal=Med Welt | year= 1975 | volume= 26 | issue= 43 | pages= 1980-8 | pmid=583-90 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=583 }} </ref> | ||
Revision as of 17:56, 8 October 2015
|
Ependymoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Ependymoma medical therapy On the Web |
|
American Roentgen Ray Society Images of Ependymoma medical therapy |
|
Risk calculators and risk factors for Ependymoma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Chemotherapy
- There is no evidence to date that adjuvant chemotherapy, including the use of myeloablative chemotherapy,[1] improves the outcome for patients with totally resected, nondisseminated ependymoma.[2]
- current treatment approaches do not include chemotherapy as a standard component of primary therapy for children with newly diagnosed ependymomas that are completely resected.
Radiation Therapy
- Radiation therapy consisting of 54 Gy to 55.8 Gy is recommended for children aged 3 years and older who are diagnosed with well-differentiated ependymomas.[3]
- It is not necessary to treat the entire CNS (whole brain and spine) because these tumors usually recur initially at the local site.[4][5]
- When possible, patients should be treated in a center experienced with the delivery of highly conformal radiation therapy (including intensity-modulated radiation therapy or charged-particle radiation therapy) to pediatric patients with brain tumors.
References
- ↑ Warth J, Desforges JF (1975). "Determinants of intracellular pH in the erythrocyte". Br J Haematol. 29 (3): 369–72. PMID 34-40 Check
|pmid=value (help). - ↑ Kozlova MV (1975). "[Differences in the responses of taste receptors to organic and inorganic acids with changes in the concentration of bicarbonate in the solution]". Fiziol Zh SSSR Im I M Sechenova. 61 (7): 1000–7. PMID 1293-301 Check
|pmid=value (help). - ↑ Diewitz M (1975). "[Coronary heart disease and its differential treatment]". Med Welt. 26 (43): 1980–8. PMID 583-90 Check
|pmid=value (help). - ↑ De Dobbeleer GD, Ledoux-Corbusier MH, Achten GA (1975). "Graft versus host reaction. An ultrastructural study". Arch Dermatol. 111 (12): 1597–902. PMID 972-8 Check
|pmid=value (help). - ↑ Colwell WM, Simmons DG, Harris JR, Fulp TG, Carrozza JH, Maag TA (1975). "Influence of some physical factors on survival of Marek's disease vaccine virus". Avian Dis. 19 (4): 781–90. PMID 987-93 Check
|pmid=value (help).