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Children oncology group (COG) risk stratification system determines the protocol of management used for neuroblastoma patients. Low risk neuroblastoma patients are managed with either observation or surgical resection of the tumor. Intermidiate risk neuroblastoma patients are managed with neoadjuvant chemotherapy in advance of a definitive surgical resection. Whereas | Children oncology group (COG) risk stratification system determines the protocol of management used for neuroblastoma patients. Low risk neuroblastoma patients are usually managed with either observation or surgical resection of the tumor. Intermidiate risk neuroblastoma patients are usually managed with neoadjuvant chemotherapy in advance of a definitive surgical resection. Whereas high risk neuroblastoma patients are usually managed with a combination of surgery, chemotherapy, radiation therapy, hematopoietic stem cell transplantation, and immunotherapy. | ||
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Children's Oncology Group Risk Stratification | Children's Oncology Group Risk Stratification | ||
A regimen of chemotherapy, surgery, SCT, radiation therapy, and anti-GD2 antibody ch14.18, with interleukin-2/GM-CSF and isotretinoin | |||
{{Family tree/start}} | {{Family tree/start}} | ||
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{{familytree | | |,|-|-|-|+|-|-|-|.| | | | }} | {{familytree | | |,|-|-|-|+|-|-|-|.| | | | }} | ||
{{familytree | | X01 | | X02 | | X03 | | | |X01=<div style="width: 20em; padding: | {{familytree | | X01 | | X02 | | X03 | | | |X01=<div style="width: 20em; padding:0em;">'''Low risk patients'''</div>| X02=<div style="width: 20em; padding:0em;">'''Intermediate risk patients'''</div>| X03=<div style="width: 20em; padding:0em;">'''High risk patients'''</div>}} | ||
{{familytree|boxstyle= border-top: 0px;| | A01 | | A02 | | A03 | | | |A01=<div style="width: 20em; padding: | {{familytree|boxstyle= border-top: 0px;| | A01 | | A02 | | A03 | | | |A01=<div style="width: 20em; padding:0em;text-align:left"> | ||
''' | *'''Surgery followed by chemotherapy''' | ||
*'''Chemotherapy with or without surgery''' | |||
*'''Observation without biopsy''' | |||
</div>|A02=<div style="width: 20em; padding:0em;text-align:left"> | |||
*'''Chemotherapy with or without surgery''' | |||
*'''Surgery and observation''' | |||
*'''Radiation therapy''' | |||
</div>|A03=<div style="width: 20em; padding:0em;text-align:left"> | |||
*'''A combination of chemotherapy, surgery, stem cell transplantation, radiation therapy, immunotherapy, and isotretinoin''' | |||
</div>}} | |||
{{Family tree/end}} | {{Family tree/end}} | ||
Revision as of 19:05, 9 October 2015
Children oncology group (COG) risk stratification system determines the protocol of management used for neuroblastoma patients. Low risk neuroblastoma patients are usually managed with either observation or surgical resection of the tumor. Intermidiate risk neuroblastoma patients are usually managed with neoadjuvant chemotherapy in advance of a definitive surgical resection. Whereas high risk neuroblastoma patients are usually managed with a combination of surgery, chemotherapy, radiation therapy, hematopoietic stem cell transplantation, and immunotherapy.
Low risk neuroblastoma patients are managed with either observation or surgical resection of the tumor.
Intermediate risk neuroblastoma patients are managed with neoadjuvant chemotherapy in advance of a definitive surgical resection.
High risk neuroblastoma patients are managed with a combination of surgery, chemotherapy, radiation therapy, hematopoietic stem cell transplantation, and immunotherapy.
Children's Oncology Group Risk Stratification
A regimen of chemotherapy, surgery, SCT, radiation therapy, and anti-GD2 antibody ch14.18, with interleukin-2/GM-CSF and isotretinoin
Children's oncology group risk stratification | |||||||||||||||||||||||||||||
Low risk patients | Intermediate risk patients | High risk patients | |||||||||||||||||||||||||||
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