Retinoblastoma risk factors: Difference between revisions
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==Common Risk Factors== | ==Common Risk Factors== | ||
==Family History== | ===Family History=== | ||
Approximately 10% of patients with retinoblastoma have a previously established family history of the disease. | Approximately 10% of patients with retinoblastoma have a previously established family history of the disease. | ||
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===Advanced paternal age=== | ===Advanced paternal age=== | ||
There is evidence suggesting that the mutations of RB1 are more common during spermatogenesis than oogenesis. | There is evidence suggesting that the mutations of RB1 are more common during spermatogenesis than oogenesis. | ||
==See also== | ==See also== | ||
*[[Eye cancer]] | *[[Eye cancer]] | ||
Revision as of 04:25, 11 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
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Overview
Common risk factors in the development of retinoblastoma are, advanced paternal age, positive family history, and viral exposure.
Common Risk Factors
Family History
Approximately 10% of patients with retinoblastoma have a previously established family history of the disease.
Viral exposure
The presence of HPV sequences in retinoblastoma tumor tissue may play a role in the development of sporadic retinoblastoma.
Advanced paternal age
There is evidence suggesting that the mutations of RB1 are more common during spermatogenesis than oogenesis.