Oligodendroglioma other imaging findings: Difference between revisions
Jump to navigation
Jump to search
| Line 12: | Line 12: | ||
*[[Choline]]-to-[[creatine]] ratio of less than 3:1 | *[[Choline]]-to-[[creatine]] ratio of less than 3:1 | ||
*Reduction of [[N-acetyl aspartate|NAA]]/[[creatine]] ratio | *Reduction of [[N-acetyl aspartate|NAA]]/[[creatine]] ratio | ||
*Increased [[choline]] levels and decreased [[N-acetyl aspartate|NAA]] levels | *Increased [[choline]] levels and decreased [[N-acetyl aspartate|NAA]] levels with a [[myo-inositol]] peak | ||
*Increased [[glutamine]] and [[glutamate]] | *Increased [[glutamine]] and [[glutamate]] levels in low-grade oligodendroglioma in contrast to high-grade oligodendroglioma | ||
*Increased [[lipid]] and [[lactate]] levels in high-grade oligodendroglioma in contrast to low-grade oligodendroglioma | |||
===Magnetic Resonance Perfusion=== | ===Magnetic Resonance Perfusion=== | ||
Revision as of 20:49, 13 October 2015
|
Oligodendroglioma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Oligodendroglioma other imaging findings On the Web |
|
American Roentgen Ray Society Images of Oligodendroglioma other imaging findings |
|
Risk calculators and risk factors for Oligodendroglioma other imaging findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other Imaging Findings
Other imaging studies for oligodendroglioma include:[1][2][3][4]
Magnetic Resonance Spectroscopy
- N-acetyl aspartate (NAA) peak is dominant
- Choline-to-creatine ratio of less than 3:1
- Reduction of NAA/creatine ratio
- Increased choline levels and decreased NAA levels with a myo-inositol peak
- Increased glutamine and glutamate levels in low-grade oligodendroglioma in contrast to high-grade oligodendroglioma
- Increased lipid and lactate levels in high-grade oligodendroglioma in contrast to low-grade oligodendroglioma
Magnetic Resonance Perfusion
- There is increased "chicken wire" network of vascularity, which results in elevated relative cerebral blood volume (rCBV).[5]
- MR perfusion has a sensitivity of 95% for distinguishing grade II from grade III oligodendrogliomas. rCBV above the threshold of 1.75 demonstrates more rapid tumor progression.
Images
-
![MR perfusion demonstrates significantly increased CBV (area 'under' the purple curve) compared to the other side.[6]](/images/7/76/MR_perfusion_oligodendroglioma_1.jpg)
MR perfusion demonstrates significantly increased CBV (area 'under' the purple curve) compared to the other side.[6] -
![MR perfusion of the brain.[6]](/images/0/0c/MR_perfusion_oligodendroglioma_2.jpg)
MR perfusion of the brain.[6]
![MR perfusion demonstrates significantly increased CBV (area 'under' the purple curve) compared to the other side.[6]](/index.php/File:MR_perfusion_oligodendroglioma_1.jpg)
![MR perfusion of the brain.[6]](/index.php/File:MR_perfusion_oligodendroglioma_2.jpg)
Positron Emission Tomography
- 11C-Methionine PET and F-18 FDG PET studies can be used to differentiate oligodendroglioma from anaplastic oligodendroglioma.[5]
- [18F]-fluorodeoxyglucose (FDG) uptake of oligodendroglioma is similar to normal white matter, whereas FDG uptake of anaplastic oligodendroglioma is similar to normal gray matter.
Bone Scan
- Most malignant gliomas get metastasized to the bones via the hematogenous spread.[7]
- Bone scan may be performed to detect metastases of malignant oligodendroglioma or anaplastic oligodendroglioma to bones.[8]
References
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Nikaido K, Nihira H, Wakai S, Honmo O, Tsuzuki A (2003). "[A case of oligodendroglioma with temporal lobe epilepsy initially suspected as having paroxymal tachycardia]". No To Hattatsu. 35 (5): 401–5. PMID 13677949.
- ↑ Axial MRS of oligodendroglioma. Dr. Bruno Di Muzio. Radiopaedia 2015. http://radiopaedia.org/cases/oligodendroglioma-14
- ↑ Rijpkema M, Schuuring J, van der Meulen Y, van der Graaf M, Bernsen H, Boerman R; et al. (2003). "Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging". NMR Biomed. 16 (1): 12–8. doi:10.1002/nbm.807. PMID 12577293.
- ↑ 5.0 5.1 Radiographic features of oligodendroglioma. Dr. Henry Knipe and Dr. Frank Gaillard et al. http://radiopaedia.org/articles/oligodendroglioma
- ↑ 6.0 6.1 Image courtesy of Dr. Frank Gaillard. Radiopaedia (original file here). Creative Commons BY-SA-NC
- ↑ Beauchesne P (2011). "Extra-neural metastases of malignant gliomas: myth or reality?". Cancers (Basel). 3 (1): 461–77. doi:10.3390/cancers3010461. PMC 3756372. PMID 24212625.
- ↑ Al-Ali F, Hendon AJ, Liepman MK, Wisniewski JL, Krinock MJ, Beckman K (2005). "Oligodendroglioma metastatic to bone marrow". AJNR Am J Neuroradiol. 26 (9): 2410–4. PMID 16219856.