Oligodendroglioma other imaging findings: Difference between revisions
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*Increased [[glutamine]] and [[glutamate]] levels in low-grade oligodendroglioma in contrast to high-grade oligodendroglioma | *Increased [[glutamine]] and [[glutamate]] levels in low-grade oligodendroglioma in contrast to high-grade oligodendroglioma | ||
*Increased [[lipid]] and [[lactate]] levels in high-grade oligodendroglioma in contrast to low-grade oligodendroglioma | *Increased [[lipid]] and [[lactate]] levels in high-grade oligodendroglioma in contrast to low-grade oligodendroglioma | ||
====Images==== | |||
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Image:MRS oligodendroglioma.jpeg|On spectroscopy, the lesion demonstrates increased choline and decreased NAA with a myo-inositol peak.<ref name=ffghj>Image courtesy of Dr. Bruno Di Muzio. Radiopaedia (original file [http://radiopaedia.org/cases/oligodendroglioma-14 here]). Creative Commons BY-SA-NC</ref> | |||
===Magnetic Resonance Perfusion=== | ===Magnetic Resonance Perfusion=== | ||
Revision as of 20:58, 13 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other Imaging Findings
Other imaging studies for oligodendroglioma include:[1][2][3][4]
Magnetic Resonance Spectroscopy
- N-acetyl aspartate (NAA) peak is dominant
- Choline-to-creatine ratio of less than 3:1
- Reduction of NAA/creatine ratio
- Increased choline levels and decreased NAA levels with a myo-inositol peak
- Increased glutamine and glutamate levels in low-grade oligodendroglioma in contrast to high-grade oligodendroglioma
- Increased lipid and lactate levels in high-grade oligodendroglioma in contrast to low-grade oligodendroglioma
Images
-
![On spectroscopy, the lesion demonstrates increased choline and decreased NAA with a myo-inositol peak.[5]](/images/0/03/MRS_oligodendroglioma.jpeg)
On spectroscopy, the lesion demonstrates increased choline and decreased NAA with a myo-inositol peak.[5] -
![MR perfusion demonstrates significantly increased CBV (area 'under' the purple curve) compared to the other side.[6]](/images/7/76/MR_perfusion_oligodendroglioma_1.jpg)
MR perfusion demonstrates significantly increased CBV (area 'under' the purple curve) compared to the other side.[6] -
![MR perfusion of the brain.[6]](/images/0/0c/MR_perfusion_oligodendroglioma_2.jpg)
MR perfusion of the brain.[6]
![On spectroscopy, the lesion demonstrates increased choline and decreased NAA with a myo-inositol peak.[5]](/index.php/File:MRS_oligodendroglioma.jpeg)
![MR perfusion demonstrates significantly increased CBV (area 'under' the purple curve) compared to the other side.[6]](/index.php/File:MR_perfusion_oligodendroglioma_1.jpg)
![MR perfusion of the brain.[6]](/index.php/File:MR_perfusion_oligodendroglioma_2.jpg)
Positron Emission Tomography
- 11C-Methionine PET and F-18 FDG PET studies can be used to differentiate oligodendroglioma from anaplastic oligodendroglioma.[7]
- [18F]-fluorodeoxyglucose (FDG) uptake of oligodendroglioma is similar to normal white matter, whereas FDG uptake of anaplastic oligodendroglioma is similar to normal gray matter.
Bone Scan
- Most malignant gliomas get metastasized to the bones via the hematogenous spread.[8]
- Bone scan may be performed to detect metastases of malignant oligodendroglioma or anaplastic oligodendroglioma to bones.[9]
References
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Nikaido K, Nihira H, Wakai S, Honmo O, Tsuzuki A (2003). "[A case of oligodendroglioma with temporal lobe epilepsy initially suspected as having paroxymal tachycardia]". No To Hattatsu. 35 (5): 401–5. PMID 13677949.
- ↑ Axial MRS of oligodendroglioma. Dr. Bruno Di Muzio. Radiopaedia 2015. http://radiopaedia.org/cases/oligodendroglioma-14
- ↑ Rijpkema M, Schuuring J, van der Meulen Y, van der Graaf M, Bernsen H, Boerman R; et al. (2003). "Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging". NMR Biomed. 16 (1): 12–8. doi:10.1002/nbm.807. PMID 12577293.
- ↑ Image courtesy of Dr. Bruno Di Muzio. Radiopaedia (original file here). Creative Commons BY-SA-NC
- ↑ 6.0 6.1 Image courtesy of Dr. Frank Gaillard. Radiopaedia (original file here). Creative Commons BY-SA-NC
- ↑ Radiographic features of oligodendroglioma. Dr. Henry Knipe and Dr. Frank Gaillard et al. http://radiopaedia.org/articles/oligodendroglioma
- ↑ Beauchesne P (2011). "Extra-neural metastases of malignant gliomas: myth or reality?". Cancers (Basel). 3 (1): 461–77. doi:10.3390/cancers3010461. PMC 3756372. PMID 24212625.
- ↑ Al-Ali F, Hendon AJ, Liepman MK, Wisniewski JL, Krinock MJ, Beckman K (2005). "Oligodendroglioma metastatic to bone marrow". AJNR Am J Neuroradiol. 26 (9): 2410–4. PMID 16219856.