Ewing's sarcoma medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
===Chemotherapy=== | ===Chemotherapy regimens=== | ||
* | *The most common chemotherapy combination used to treat Ewing sarcoma is: | ||
:*[[Vincristine]], [[doxorubicin]], and [[cyclophosphamide]] alternating with [[ifosfamide]] and [[etoposide]]. | |||
* Because almost all patients with apparently localized disease at diagnosis have occult metastatic disease, multi drug [[chemotherapy]] as well as local disease control with surgery and/or radiation is indicated in the treatment of all patients. Treatment often consists of neo-adjuvant [[chemotherapy]] generally followed by wide or radical excision, and may also include [[radiotherapy]]. | * Because almost all patients with apparently localized disease at diagnosis have occult metastatic disease, multi drug [[chemotherapy]] as well as local disease control with surgery and/or radiation is indicated in the treatment of all patients. Treatment often consists of neo-adjuvant [[chemotherapy]] generally followed by wide or radical excision, and may also include [[radiotherapy]]. | ||
* Treatment lengths vary depending on location and stage of the disease at diagnosis. Radical chemotherapy may be as short as 6 treatments at 3 week cycles, however most patients will undergo chemotherapy for 6-12 months and radiation therapy for 5-8 weeks. | * Treatment lengths vary depending on location and stage of the disease at diagnosis. Radical chemotherapy may be as short as 6 treatments at 3 week cycles, however most patients will undergo chemotherapy for 6-12 months and radiation therapy for 5-8 weeks. | ||
Revision as of 14:36, 15 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with Ewing's sarcoma have many treatment options. The selection depends on the stage of the tumor. The options are surgery, radiation therapy, chemotherapy, or a combination of these methods. Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects may not be the same for each person, and they may change from one treatment session to the next.
Medical Therapy
Chemotherapy regimens
- The most common chemotherapy combination used to treat Ewing sarcoma is:
- Vincristine, doxorubicin, and cyclophosphamide alternating with ifosfamide and etoposide.
- Because almost all patients with apparently localized disease at diagnosis have occult metastatic disease, multi drug chemotherapy as well as local disease control with surgery and/or radiation is indicated in the treatment of all patients. Treatment often consists of neo-adjuvant chemotherapy generally followed by wide or radical excision, and may also include radiotherapy.
- Treatment lengths vary depending on location and stage of the disease at diagnosis. Radical chemotherapy may be as short as 6 treatments at 3 week cycles, however most patients will undergo chemotherapy for 6-12 months and radiation therapy for 5-8 weeks.