Glucagonoma natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
For approximately 60% of these tumors are cancerous, the prognosis of glucagonoma depends on the following: | For approximately 60% of these tumors are cancerous, the prognosis of glucagonoma depends on the following: | ||
*Whether or not the tumor can be removed by surgery | *Whether or not the tumor can be removed by surgery | ||
*The stage of the tumor, the size of the tumor, whether the cancer has spread outside the pancreas | *The stage of the tumor, the size of the tumor, whether the cancer has spread outside the pancreas | ||
*The patient’s general health | *The patient’s general health | ||
*Whether the tumor has just been diagnosed or has recurred | *Whether the tumor has just been diagnosed or has recurred | ||
*The presence of metastasis is associated with a particularly poor prognosis among patients with glucagonoma. The 10 year event free survival rate is less than 51.6% with metastasis and 64.3% without metastasis | *The presence of metastasis is associated with a particularly poor prognosis among patients with glucagonoma. The 10 year event free survival rate is less than 51.6% with metastasis and 64.3% without metastasis | ||
==References== | ==References== | ||
Revision as of 14:25, 16 October 2015
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Glucagonoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
If left untreated, patients with glucagonoma may progress to develop necrolytic migratory erythema, cheilosis, stomatitis, diarrhea, polyuria, and polydipsia. The presence of metastasis is associated with a particularly poor prognosis among patients with glucagonoma. The 10 year event free survival rate is less than 51.6% with metastasis and 64.3% without metastasis.
Natural History
- If left untreated, patients with glucagonoma may progress to develop necrolytic migratory erythema, cheilosis, stomatitis, diarrhea, polyuria, and polydipsia.
- They have a very slow growth rate compared to most malignant tumors.
Prognosis
For approximately 60% of these tumors are cancerous, the prognosis of glucagonoma depends on the following:
- Whether or not the tumor can be removed by surgery
- The stage of the tumor, the size of the tumor, whether the cancer has spread outside the pancreas
- The patient’s general health
- Whether the tumor has just been diagnosed or has recurred
- The presence of metastasis is associated with a particularly poor prognosis among patients with glucagonoma. The 10 year event free survival rate is less than 51.6% with metastasis and 64.3% without metastasis
References