Oligoastrocytoma pathophysiology: Difference between revisions

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Revision as of 15:11, 16 October 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Development of oligoastrocytoma is the result of multiple genetic mutations.
Oligoastrocytomas are mixed tumors that have molecular genetics that overlap with both oligodendrogliomas and astrocytomas.
Genes associated with the pathogenesis of oligoastrocytoma include:

On microscopic histopathological analysis, oligoastrocytoma is characterized by:

On microscopic histopathological analysis, anaplastic oligoastrocytoma is characterized by:

Oligoastrocytoma is demonstrated by positivity to tumor markers such as:^[1]

↑ IHC of oligoastrocytoma. Librepathology 2015. http://librepathology.org/wiki/index.php/Oligoastrocytoma. Accessed on October 16, 2015

@@ Line 10: / Line 10: @@
 ===Genetics===
 *Development of oligoastrocytoma is the result of multiple [[mutation|genetic mutations]].
+*Oligoastrocytomas are mixed tumors that have molecular genetics that overlap with both [[oligodendrogliomas]] and [[astrocytomas]].
 *Genes associated with the pathogenesis of oligoastrocytoma include:
 :*''[[Isocitrate dehydrogenase|IDH1]]''
 :*[[translocation|t(1;19)(q10;p10)]]