Anaplastic large cell lymphoma laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory tests for anaplastic large cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[FISH]], [[immunohistochemistry]], and [[immunophenotyping]]. | Laboratory tests for anaplastic large cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[flow cytometry]], [[FISH]], [[immunohistochemistry]], and [[immunophenotyping]]. | ||
===Laboratory Findings<ref name="ALK+/ALK-">{{cite web|url=http://www.bloodjournal.org/content/111/12/5496?sso-checked=true|title=ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project}}</ref>=== | ===Laboratory Findings<ref name="ALK+/ALK-">{{cite web|url=http://www.bloodjournal.org/content/111/12/5496?sso-checked=true|title=ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project}}</ref>=== | ||
Laboratory tests for anaplastic large cell lymphoma include: | Laboratory tests for anaplastic large cell lymphoma include: | ||
| Line 11: | Line 11: | ||
* Blood chemistry studies | * Blood chemistry studies | ||
:* Increased [[LDH]] | :* Increased [[LDH]] | ||
* [[Flow cytometry]] | |||
* Fluorescence in situ hybridization ([[FISH]]) <ref> Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015</ref> | * Fluorescence in situ hybridization ([[FISH]]) <ref> Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015</ref> | ||
:* Negative for the Epstein-Barr virus ([[EBV]]) | :* Negative for the Epstein-Barr virus ([[EBV]]) | ||
Revision as of 18:56, 16 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Laboratory tests for anaplastic large cell lymphoma include complete blood count (CBC), blood chemistry studies, flow cytometry, FISH, immunohistochemistry, and immunophenotyping.
Laboratory Findings[1]
Laboratory tests for anaplastic large cell lymphoma include:
- Complete blood count (CBC)
- Blood chemistry studies
- Increased LDH
- Flow cytometry
- Fluorescence in situ hybridization (FISH) [2]
- Negative for the Epstein-Barr virus (EBV)
- Negative for human herpes virus-8 (HHV8)
- Immunophenotyping[3]
References
- ↑ "ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project".
- ↑ Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015
- ↑ Dovepress. Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature . https://www.dovepress.com/anaplastic-lymphoma-kinase-positive-anaplastic-large-cell-lymphoma-wit-peer-reviewed-article-OTT Accessed on October 13, 2015