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* Patients of all age groups may develop anapastic large cell lymphoma  
* Patients of all age groups may develop anapastic large cell lymphoma  
* Anaplastic large cell lymphoma  is a common disease that tends to affect children or young adults
* Anaplastic large cell lymphoma  is a common disease that tends to affect children or young adults
* Anaplastic large cell lymphoma, ALK-positive usually affects younger individuals
* Anaplastic large cell lymphoma, ALK-positive usually affects younger individuals (between 10 and 29 years)<ref name="pmid11090048">{{cite journal| author=Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K et al.| title=CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features. | journal=Blood | year= 2000 | volume= 96 | issue= 12 | pages= 3681-95 | pmid=11090048 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11090048  }} </ref>
* Anaplastic large cell lymphoma, ALK-negative usually affects older individuals
* Anaplastic large cell lymphoma, ALK-negative usually affects older individuals (between 40-60 years)
===Gender<small><ref Name= Cancer.ca> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 7, 2015</ref></small>===
===Gender<small><ref Name= Cancer.ca> Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 7, 2015</ref></small>===
* Males are more commonly affected with anaplastic large cell lymphoma than females
* Males are more commonly affected with anaplastic large cell lymphoma than females
== Epidemiology and Demographics==
ALK negative ALCL represents 2%-3% of all [[non-Hodgkin's lymphomas]] ([[NHL]]) and 12% of all [[T-cell NHL]].<ref name="ALK">{{cite web|url=http://www.sciencedirect.com/science/article/pii/S104084281200131X|title=Anaplastic large cell lymphoma, ALK-negative}}</ref>
===Age===
ALK negative ALCL affects primarily adults between 40-60 years old.
===Gender===
There is a modest male predominance in the prevalence of the disease.<ref name=Swerdlow>{{cite book | last = Swerdlow | first = Steven | title = WHO classification of tumours of haematopoietic and lymphoid tissues | publisher = International Agency for Research on Cancer | location = Lyon, France | year = 2008 | isbn = 9789283224310 }}</ref>
ALK positive anaplastic large cell lymphoma affects primarily young (between 10 and 29 years), male patients<ref name="pmid11090048">{{cite journal| author=Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K et al.| title=CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features. | journal=Blood | year= 2000 | volume= 96 | issue= 12 | pages= 3681-95 | pmid=11090048 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11090048  }} </ref> and accounts for 3% of all [[NHL]], 40% of all large cell lymphomas<ref>{{cite web|url=http://www.bloodjournal.org/content/93/8/2697?sso-checked=true|title=ALK+ Lymphoma: Clinico-Pathological Findings and Outcome}}</ref> and 10%-20% of childhood lymphomas.<ref>{{cite web|url=http://www.bloodjournal.org/content/93/8/2697?sso-checked=true|title=ALK+ Lymphoma: Clinico-Pathological Findings and Outcome}}</ref>
According to a study on 1,320 cases of [[peripheral T-cell lymphomas]] and NK cell lymphomas between 1990 and 2002 in 22 different centers, ALK-Positive ALCL is the fifth most common type of peripheral T cell lymphoma (6.6% of total patients).<ref>{{cite web|url=http://jco.ascopubs.org/content/26/25/4124.full.pdf|title=International Peripheral T-Cell and Natural Killer/T-Cell Lymphoma Study: Pathology Findings and Clinical Outcomes}}</ref>  In the United states, ALK-Positive ALCL is the most frequent type of [[peripheral T-cell lymphoma]].


==References==
==References==

Revision as of 15:31, 19 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Anaplastic large cell lymphoma is a common disease that tends to affect children or young adults. Males are more commonly affected with anaplastic large cell lymphoma than females.[1]

Epidemiology and Demographics

Age[1]

  • Patients of all age groups may develop anapastic large cell lymphoma
  • Anaplastic large cell lymphoma is a common disease that tends to affect children or young adults
  • Anaplastic large cell lymphoma, ALK-positive usually affects younger individuals (between 10 and 29 years)[2]
  • Anaplastic large cell lymphoma, ALK-negative usually affects older individuals (between 40-60 years)

Gender[1]

  • Males are more commonly affected with anaplastic large cell lymphoma than females

References

  1. ↑ 1.0 1.1 1.2 Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 7, 2015
  2. ↑ Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K; et al. (2000). "CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features". Blood. 96 (12): 3681–95. PMID 11090048.

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