Sandbox:classification 1: Difference between revisions
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{{familytree | | | | A02 | | | | | | A03 | | | | | | | A02=<div style="width: 25em; padding:0.5em;">'''Hairy cell leukemia'''</div>|A03=<div style="width: 25em; padding:0.5em;">'''Hairy cell leukemia variant'''</div>}} | {{familytree | | | | A02 | | | | | | A03 | | | | | | | A02=<div style="width: 25em; padding:0.5em;">'''Hairy cell leukemia'''</div>|A03=<div style="width: 25em; padding:0.5em;">'''Hairy cell leukemia variant'''</div>}} | ||
{{familytree|boxstyle= border-top: 0px; | | | | A02 | | | | | | A03 | | | | | | | | | A02=<div style="width: 25em; padding:0.5em;text-align:left">''' | {{familytree|boxstyle= border-top: 0px; | | | | A02 | | | | | | A03 | | | | | | | | | A02=<div style="width: 25em; padding:0.5em;text-align:left"> | ||
* '''Occurs in approximately 95% of the cases'''<br> | |||
* '''The male to female ratio is approximately 4 to 1'''<br> | |||
* '''The median age at diagnosis is 55 years'''<br>'''Less than 10% lymphocytosis on peripheral blood smear'''<br>'''Decreased level of monocyte on peripheral blood smear'''<br>'''Decreased hemoglobin level in approximately 85% of the patients'''<br>'''Thrombocytopenia is present in approximately 80% of the patients'''<br>'''CD103 +, CD11c +, CD25 +'''<br>'''DBA.44 + Cyclin D1 + Annexin A1 + on immunohistochemistry'''<br>'''Presence of BRAF V600E mutation on cytogenetic tests'''</div> | |||
|A03=<div style="width: 25em; padding:0.5em; text-align:left">'''Occurs in approximately 5% of the cases '''<br>'''The male to female ratio is approximately 2 to 1'''<br>'''The median age at diagnosis is greater than 70 years.'''<br>'''Less than 10% lymphocytosis on peripheral blood smear'''<br>'''Normal level of monocyte on peripheral blood smear'''<br>'''Normal hemoglobin level in most of the patients'''<br>'''Normal platelets count in most of the patients'''<br>'''CD103 +, CD11c +, CD25 - on immunophenotype'''<br>'''DBA.44 + Cyclin D1 + Annexin A1 - on immunohistochemistry'''<br>'''Presence of BRAF wild type on cytogenetic tests'''</div>}} | |||
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The median age at diagnosis is 55 years. |
Revision as of 18:50, 19 October 2015
Hairy cell leukemia classification | |||||||||||||||||||||||||||||||||||||||||||
Hairy cell leukemia | Hairy cell leukemia variant | ||||||||||||||||||||||||||||||||||||||||||
| Occurs in approximately 5% of the cases The male to female ratio is approximately 2 to 1 The median age at diagnosis is greater than 70 years. Less than 10% lymphocytosis on peripheral blood smear Normal level of monocyte on peripheral blood smear Normal hemoglobin level in most of the patients Normal platelets count in most of the patients CD103 +, CD11c +, CD25 - on immunophenotype DBA.44 + Cyclin D1 + Annexin A1 - on immunohistochemistry Presence of BRAF wild type on cytogenetic tests | ||||||||||||||||||||||||||||||||||||||||||
The median age at diagnosis is 55 years.