Myeloproliferative neoplasm causes: Difference between revisions

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{{CMG}}{{AE}} {{MJK}}
{{CMG}}{{AE}} {{MJK}}
==Overview==
==Overview==
Myeloproliferative disease is caused by a mutation in the ''[[BCR]]-[[ABL]]'', ''[[Janus kinase 2]]'', and [[calreticulin]] genes.<ref name="ganfyd">Ganfyd. Polycythaemia vera 2015.http://www.ganfyd.org/index.php?title=Polycythemia_vera</ref><ref name="pmidhttp://dx.doi.org/10.1182/blood-2013-11-538983">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=http://dx.doi.org/10.1182/blood-2013-11-538983 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10  }} </ref><ref name="ganfyd">Ganfyd. Myelofibrosis2015.http://www.ganfyd.org/index.php?title=Primary_myelofibrosis</ref>
Myeloproliferative disease is caused by a mutation in the ''[[BCR]]-[[ABL]]'', [[Janus kinase 2]], and [[calreticulin]] genes.<ref name="ganfyd">Ganfyd. Polycythaemia vera 2015.http://www.ganfyd.org/index.php?title=Polycythemia_vera</ref><ref name="pmidhttp://dx.doi.org/10.1182/blood-2013-11-538983">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=http://dx.doi.org/10.1182/blood-2013-11-538983 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10  }} </ref><ref name="ganfyd">Ganfyd. Myelofibrosis2015.http://www.ganfyd.org/index.php?title=Primary_myelofibrosis</ref>
==Causes==
Myeloproliferative disease may be caused by a mutation in the following genes:
*''[[BCR]]-[[ABL]]''
*[[Janus kinase 2]]
*[[calreticulin]]
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 20:54, 20 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Myeloproliferative disease is caused by a mutation in the BCR-ABL, Janus kinase 2, and calreticulin genes.[1][2][1]

Causes

Myeloproliferative disease may be caused by a mutation in the following genes:

References

  1. 1.0 1.1 Ganfyd. Polycythaemia vera 2015.http://www.ganfyd.org/index.php?title=Polycythemia_vera
  2. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID http://dx.doi.org/10.1182/blood-2013-11-538983 Check |pmid= value (help).

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