Sandbox Maliha

Condition	Ages Affected	Duration	Pathophysiology	Location	Diagnostic tests
[[Pilocytic Astrocytoma]	Sudden (acute)	2-10 minutes	Heaviness, pressure, tightness, squeezing, burning (Levine's sign)	Retrosternal	Exertion, emotions, cold	Rest, sublingual nitroglycerine (within minutes)	Radiation to neck, jaw, shoulders, or arms (commonly on left)	Sweating, nausea, palpitations, dizziness, shortness of breath, sense of impending doom
Diffuse Astrocytoma	Acute	10-20 minutes	Same as stable angina but often more severe	Same as stable angina	Same as stable angina but occurs with lower levels of exertion & rest	Same as stable angina	Same as stable angina	Same as stable angina
Anaplastic Astrocytoma	Acute	Commonly > 20 minutes	Same as stable angina but often more severe	Same as stable angina	Same as stable angina but occurs with lower levels of exertion & rest	Usually unrelieved by nitroglycerine and rest	Same as stable angina	Same as stable angina
Glioblastoma	Acute, recurrent episodes of angina	Same as stable angina	Same as stable angina	Same as stable angina	Same as stable angina	Same as stable angina	Same as stable angina	Not specific
Aortic Dissection	Sudden severe progressive pain (common) or chronic (rare)	Variable	Tearing, ripping sensation, knife like	Depends on area of dissection	Variable	Unrelenting pain, unrelieved by nitroglycerine and rest	Radiating to back, between shoulder blades (dissection in ascending aorta)	Trauma, Surgical manipulation, pregnancy, hypertension, connective tissue disease like marfan's syndrome (cystic medial degeneration)
Pericarditis	Acute or subacute	May last for hours to days	Sharp, localized	Retrosternal	Increases with coughing, deep breathing, supine position	Relieved by sitting up and leaning forward	Radiation to shoulder, neck, back abdomen	Not specific