Renal oncocytoma pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings | On gross pathology, tan or mahogany brown, well circumscribed [[tumor]], and central scar are characteristic findings of renal oncocytoma. On microscopic histopathological analysis, oncocytes and large [[eosinophilic]] cells are characteristic findings of renal oncocytoma.<ref name="pmid2028856">{{cite journal |vauthors=Palmer WE, Chew FS |title=Renal oncocytoma |journal=AJR Am J Roentgenol |volume=156 |issue=6 |pages=1144 |year=1991 |pmid=2028856 |doi=10.2214/ajr.156.6.2028856 |url=http://www.ajronline.org/doi/abs/10.2214/ajr.156.6.2028856}}</ref> | ||
==Pathogenesis== | ==Pathogenesis== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
On gross pathology, tan or mahogany brown, well circumscribed tumor, and central scar are characteristic findings of renal oncocytoma. On microscopic histopathological analysis, oncocytes and large eosinophilic cells are characteristic findings of renal oncocytoma.[1]
Pathogenesis
- Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.[2]
Gross Pathology
- The tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter).[2]
Microscopic Pathology
- An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli with excessive amounts of mitochondria.[1]
References
- ↑ 1.0 1.1 Palmer WE, Chew FS (1991). "Renal oncocytoma". AJR Am J Roentgenol. 156 (6): 1144. doi:10.2214/ajr.156.6.2028856. PMID 2028856.
- ↑ 2.0 2.1 Velasquez G, Glass TA, D'Souza VJ, Formanek AG (1984). "Multiple oncocytomas and renal carcinoma". AJR Am J Roentgenol. 142 (1): 123–4. doi:10.2214/ajr.142.1.123. PMID 6606945.